{"id":"W3094378719","doi":"10.1089/cap.2020.0109","title":"Efficacy and Safety of Multilayer, Extended-Release Methylphenidate (PRC-063) in Children 6–12 Years of Age with Attention-Deficit/Hyperactivity Disorder: A Laboratory Classroom Study","year":2020,"lang":"en","type":"article","venue":"Journal of Child and Adolescent Psychopharmacology","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Purdue Pharma (Canada)","funders":"","keywords":"Placebo; Methylphenidate; Attention deficit hyperactivity disorder; Randomized controlled trial; Adverse effect; Confidence interval; Medicine; Rating scale; Psychology; Pediatrics; Anesthesia; Internal medicine; Psychiatry; Developmental psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001367997,0.0008932129,0.001860749,0.0002935586,0.0004014422,0.0003756856,0.0009739297,0.0008656131,0.00184657],"category_scores_gemma":[0.001275205,0.0004316825,0.0007625722,0.0002048379,0.0006715197,0.0005219727,0.0003316651,0.00148067,0.0004466039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004654431,"about_ca_system_score_gemma":0.0009849938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001315561,"about_ca_topic_score_gemma":0.002430193,"domain_scores_codex":[0.9992297,0.0003325816,0.00006960162,0.0001278204,0.000171355,0.00006899711],"domain_scores_gemma":[0.9987854,0.0002473897,0.0003741591,0.00009561792,0.000138588,0.0003589352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5572268,0.165165,0.02744185,0.001756062,0.00134383,0.0005809426,0.0006285298,0.0009058632,0.1312937,0.0000655962,0.0009757274,0.1126161],"study_design_scores_gemma":[0.1115809,0.8056858,0.06666983,0.00005563609,0.0005664264,0.0005410265,0.0001432708,0.0007042827,0.01293,0.00002399892,0.001062478,0.00003638082],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989434,0.0004273126,0.0001045012,0.00003330682,0.00001317677,0.0002094573,0.0001027525,0.00002197105,0.0001441798],"genre_scores_gemma":[0.9967113,0.0008573614,0.001130187,0.0001310207,0.00005379284,0.0003319415,0.0004024453,0.00001025154,0.0003717147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001860749,"threshold_uncertainty_score":0.007234752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01331963802373403,"score_gpt":0.3060291396120723,"score_spread":0.2927095015883383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}