{"id":"W3094406399","doi":"10.1038/s41598-020-74961-6","title":"In vitro maturation in the presence of Leukemia Inhibitory Factor modulates gene and miRNA expression in bovine oocytes and embryos","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Ministerio de Ciencia y Tecnología; Ministerio de Ciencia e Innovación; Generalitat de Catalunya","keywords":"Blastocyst; Leukemia inhibitory factor; Embryo; Andrology; Oocyte; In vitro maturation; Gene expression; Biology; Molecular biology; Embryogenesis; Cell biology; Gene; Embryonic stem cell; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001747807,0.0001394971,0.0002842091,0.0001092173,0.000114507,0.0003399327,0.0001264623,0.0001356959,0.0006473745],"category_scores_gemma":[0.0001719467,0.0001115264,0.0002135859,0.00007207452,0.0001103085,0.000144527,0.0001556156,0.0003382616,0.0002483534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002584279,"about_ca_system_score_gemma":0.000174924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001128049,"about_ca_topic_score_gemma":0.001831126,"domain_scores_codex":[0.9998394,0.00002873625,0.00002207152,0.00003830274,0.00003731469,0.00003412101],"domain_scores_gemma":[0.9999292,0.00001407916,0.00002483022,0.000006798894,0.00001469025,0.00001048936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005765969,0.000005153051,0.0001366966,0.00002413465,0.00000154999,0.0000145093,0.00002002194,0.00001580585,0.9993344,0.00001580481,0.00001101042,0.0003632044],"study_design_scores_gemma":[0.00001657055,0.0003077742,0.009825055,0.00001602326,0.00002248627,0.0001416875,0.00007298165,0.0005299631,0.9844462,0.00003775166,0.004576643,0.000006851315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869688,0.00703881,0.002985757,0.00009342979,0.00005448536,0.000048324,0.0004716647,0.00004658812,0.002292192],"genre_scores_gemma":[0.992285,0.00202946,0.002650162,0.00008694836,0.00001820086,0.00007267621,0.0006127397,0.00002637535,0.002218442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001128049,"threshold_uncertainty_score":0.002243042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01449924464546044,"score_gpt":0.2284033201611207,"score_spread":0.2139040755156603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}