{"id":"W3094406399","doi":"10.1038/s41598-020-74961-6","title":"In vitro maturation in the presence of Leukemia Inhibitory Factor modulates gene and miRNA expression in bovine oocytes and embryos","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Ministerio de Ciencia y Tecnología; Ministerio de Ciencia e Innovación; Generalitat de Catalunya","keywords":"Blastocyst; Leukemia inhibitory factor; Embryo; Andrology; Oocyte; In vitro maturation; Gene expression; Biology; Molecular biology; Embryogenesis; Cell biology; Gene; Embryonic stem cell; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006634583,0.00008980538,0.0001872879,0.0001095701,0.00005445881,0.00003070151,0.00007177693,0.00008841186,0.00001615632],"category_scores_gemma":[0.0002248079,0.00006137005,0.00001687923,0.0002310295,0.00020931,0.00023233,0.00006973651,0.0001362083,0.000001790966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001821083,"about_ca_system_score_gemma":0.00004957535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009637906,"about_ca_topic_score_gemma":0.00002288568,"domain_scores_codex":[0.998663,0.0002348099,0.0004086687,0.0004961953,0.00005826661,0.0001390811],"domain_scores_gemma":[0.9994311,0.00006493915,0.0001801913,0.0002756526,0.00003565341,0.00001244831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009709228,0.00001480388,0.02302511,0.00005729445,0.000002366165,0.00004864276,0.006121092,0.000008382834,0.9698448,0.000001562442,0.0004684814,0.0003103289],"study_design_scores_gemma":[0.0002110094,0.00002360953,0.1609354,0.00009771332,0.000001649857,0.00008461245,0.0003624369,0.000015735,0.8376911,0.0002738914,0.0002431236,0.00005970937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865058,0.01198771,0.000005391697,0.0001898857,0.0008722633,0.0003782164,0.000003765728,0.000006138494,0.00005080269],"genre_scores_gemma":[0.9996442,0.00002242332,0.00003852021,0.00001336901,0.00001777945,0.00001641821,0.00002001036,0.000003856877,0.000223375],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1379103,"threshold_uncertainty_score":0.2502598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01449924464546044,"score_gpt":0.2284033201611207,"score_spread":0.2139040755156603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}