{"id":"W3094439767","doi":"10.1152/ajpregu.00215.2020","title":"Use of a carbonic anhydrase Ca17a knockout to investigate mechanisms of ion uptake in zebrafish (<i>Danio rerio</i>)","year":2020,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Danio; Zebrafish; Mutant; Carbonic anhydrase; Gene knockdown; Biology; Carbonic anhydrase II; Chemistry; Biochemistry; Cell biology; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002842083,0.0006077291,0.0003926449,0.000471661,0.0004503467,0.000381427,0.0005314925,0.0006641533,0.002632941],"category_scores_gemma":[0.0001878556,0.0003570487,0.000729552,0.0001375165,0.0005499387,0.0003550131,0.0005117069,0.001058022,0.0007373393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007887456,"about_ca_system_score_gemma":0.0008088891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009231455,"about_ca_topic_score_gemma":0.0126026,"domain_scores_codex":[0.9997097,0.00001863994,0.00003990626,0.0000905991,0.00007842231,0.00006270357],"domain_scores_gemma":[0.9996787,0.00003406744,0.0001178094,0.00003024899,0.00004038038,0.0000987268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004190229,0.00001029174,0.0002294584,0.00003869678,0.000004792591,0.000102655,0.00002171262,0.00004291238,0.9988968,0.0001067049,0.00004286534,0.0004612084],"study_design_scores_gemma":[0.00003907141,0.0003290496,0.008268473,0.00002560671,0.00005455064,0.0004269368,0.0001140937,0.001194102,0.9848969,0.00008991436,0.004538486,0.00002275237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825239,0.001005517,0.009530092,0.0004147739,0.0001885383,0.0002026556,0.002428315,0.0003677666,0.003338469],"genre_scores_gemma":[0.9666079,0.00110704,0.01170745,0.0002984852,0.000022935,0.000382806,0.001553699,0.0003017,0.01801795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009231455,"threshold_uncertainty_score":0.01835543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04256061407204352,"score_gpt":0.2547559579518544,"score_spread":0.2121953438798108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}