{"id":"W3094492339","doi":"10.1242/jcs.252015","title":"<i>Vibrio cholerae</i> cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy","year":2020,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Kempestiftelserna; European Research Council; Knut och Alice Wallenbergs Stiftelse; Cancerfonden","keywords":"Autophagy; Biology; Lipid-anchored protein; Cell biology; Vibrio cholerae; ATG5; BAG3; Innate immune system; Microbiology; Immune system; Bacteria; Biochemistry; Immunology; Apoptosis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001653582,0.000141116,0.0004007116,0.0001529894,0.0001012111,0.00004892045,0.0004656146,0.00008699603,0.00007882094],"category_scores_gemma":[0.000425587,0.00009234159,0.0001672775,0.0008923323,0.0004815211,0.0003204226,0.00007044106,0.0006269519,0.000007446259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000102794,"about_ca_system_score_gemma":0.001824503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005818495,"about_ca_topic_score_gemma":0.000007954965,"domain_scores_codex":[0.9972617,0.0001378458,0.0008489486,0.000238007,0.001189142,0.0003243597],"domain_scores_gemma":[0.9985583,0.0001734492,0.0005657279,0.0002073362,0.0002038572,0.0002913396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000443582,0.0003070075,0.0005674259,0.00003940427,0.000009165159,0.000439886,0.002323711,0.0001135925,0.9933726,0.0001020054,0.0001984164,0.002083221],"study_design_scores_gemma":[0.003294049,0.00123107,0.05687321,0.0001953468,0.00004761653,0.0002176193,0.0004178499,0.001304698,0.9353732,0.0001054132,0.000816726,0.0001231401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929763,0.0004032147,0.0002149757,0.003536762,0.0001615475,0.0001997857,0.000004026213,0.000008824898,0.002494573],"genre_scores_gemma":[0.9960178,0.00006657637,0.0006860705,0.002727473,0.0004681823,0.00000228359,9.715428e-7,0.000009694965,0.0000209621],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05799932,"threshold_uncertainty_score":0.3765581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02479412353702453,"score_gpt":0.2915220612695534,"score_spread":0.2667279377325289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}