{"id":"W3094516283","doi":"10.1101/2020.10.22.350199","title":"Phosphorylation of the RB C-terminus regulates condensin II release from chromatin","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Cancer Care Ontario; Western University","funders":"","keywords":"Phosphorylation; Cell biology; Chromatin; Biology; Jurkat cells; Hyperphosphorylation; Cyclin-dependent kinase; Cyclin-dependent kinase 1; Cell cycle; Chemistry; Molecular biology; Genetics; DNA; Cell; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006296288,0.0001787331,0.00009561129,0.00008144217,0.00009391824,0.0001584169,0.00008974829,0.0000960686,0.001796769],"category_scores_gemma":[0.00005888669,0.00007027297,0.0001187517,0.00006800674,0.0001571213,0.00007337082,0.0001083522,0.000235017,0.0004248047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002133978,"about_ca_system_score_gemma":0.0001246788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000544352,"about_ca_topic_score_gemma":0.0006485417,"domain_scores_codex":[0.9999551,0.000006242641,0.000003276972,0.00001005737,0.000006870102,0.00001845442],"domain_scores_gemma":[0.9999639,0.00000629089,0.00001290745,0.000003763691,0.000001956746,0.00001125591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001574948,0.00001135101,0.000109254,0.000009226039,0.000001167829,0.00002109047,0.000003567792,0.00002477661,0.9993254,0.00005335918,0.00001724746,0.0002660949],"study_design_scores_gemma":[0.00001404025,0.00006543259,0.002382324,0.00000149583,0.000002740238,0.00004701858,0.00000885034,0.0004520482,0.9966364,0.00002412306,0.0003644028,0.000001216544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997851,0.0002877401,0.0006716516,0.00004578094,0.00001090359,0.000009773741,0.0002341098,0.00002254019,0.0008666321],"genre_scores_gemma":[0.9978927,0.0001746491,0.0004561092,0.00001932821,0.000003025232,0.000009628553,0.0001984843,0.000008323272,0.001237757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001796769,"threshold_uncertainty_score":0.00601083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01293678433496904,"score_gpt":0.211971622408555,"score_spread":0.199034838073586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}