{"id":"W3094592496","doi":"10.1111/cea.13765","title":"INEXAS: A Phase 2 Randomized Trial of On‐demand Inhaled Interferon Beta‐1a in Severe Asthmatics","year":2020,"lang":"en","type":"article","venue":"Clinical & Experimental Allergy","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"AstraZeneca Canada; AstraZeneca","keywords":"Medicine; Asthma; Placebo; Exacerbation; Internal medicine; Randomized controlled trial; Sputum; Clinical endpoint; Respiratory tract infections; Inhalation; Interim analysis; Immunology; Anesthesia; Respiratory system; Tuberculosis; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002097074,0.001949553,0.004117885,0.0005284436,0.0004779976,0.001423447,0.001121038,0.001872465,0.008474594],"category_scores_gemma":[0.001732879,0.0007432115,0.002046107,0.0004107712,0.001074943,0.001132005,0.00055544,0.003256934,0.001159538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006020278,"about_ca_system_score_gemma":0.001364556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000734344,"about_ca_topic_score_gemma":0.001977739,"domain_scores_codex":[0.9991455,0.0005172542,0.00004478736,0.000112417,0.00006384079,0.0001161454],"domain_scores_gemma":[0.9991855,0.000218999,0.0001673164,0.00008014649,0.00005959425,0.0002884422],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9817313,0.005329012,0.0002430716,0.0004946159,0.0005283785,0.0000292742,0.00002599982,0.000186703,0.001749571,0.00009357779,0.0004765767,0.009111979],"study_design_scores_gemma":[0.9756508,0.02338124,0.0003663491,0.00001369949,0.0001213308,0.0000115976,0.000008468191,0.0001173013,0.00009034703,0.00005109945,0.0001823513,0.000005255017],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9783381,0.005254284,0.0008562667,0.001087347,0.001117626,0.009038991,0.001810242,0.0002201978,0.002276959],"genre_scores_gemma":[0.9593684,0.004479392,0.003465522,0.002356119,0.001118006,0.01995426,0.002519846,0.00005487365,0.006683592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008474594,"threshold_uncertainty_score":0.02835029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06103405796791655,"score_gpt":0.4050623304814818,"score_spread":0.3440282725135652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}