{"id":"W3094592496","doi":"10.1111/cea.13765","title":"INEXAS: A Phase 2 Randomized Trial of On‐demand Inhaled Interferon Beta‐1a in Severe Asthmatics","year":2020,"lang":"en","type":"article","venue":"Clinical & Experimental Allergy","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"AstraZeneca Canada; AstraZeneca","keywords":"Medicine; Asthma; Placebo; Exacerbation; Internal medicine; Randomized controlled trial; Sputum; Clinical endpoint; Respiratory tract infections; Inhalation; Interim analysis; Immunology; Anesthesia; Respiratory system; Tuberculosis; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004444989,0.0002604012,0.001591419,0.00007367835,0.00002625839,0.00001061474,0.000158525,0.0001883403,0.0007845151],"category_scores_gemma":[0.0007090979,0.00019121,0.0006373949,0.0001517413,0.0003929623,0.00005996582,0.0001214246,0.0003254425,0.00006160762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003709039,"about_ca_system_score_gemma":0.0001325745,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006364838,"about_ca_topic_score_gemma":0.000001561047,"domain_scores_codex":[0.9968554,0.0005001741,0.001651752,0.0004144709,0.0003486376,0.0002295101],"domain_scores_gemma":[0.9983171,0.000618235,0.000302882,0.0002723222,0.00004302439,0.0004464761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9836394,0.007791833,0.00005118878,0.00005418369,0.0002552202,0.0002178227,0.0007421405,0.00001178451,0.001956576,0.0001465843,0.001438591,0.00369463],"study_design_scores_gemma":[0.9672651,0.01822611,0.00004020431,0.0002385626,0.00005962529,0.00000779691,0.0008199061,0.0009203782,0.008317707,0.00002381146,0.00387425,0.0002065971],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941563,0.0009397276,0.0000632116,0.0008727189,0.0003152041,0.001415408,0.00001239262,0.00004496007,0.002180082],"genre_scores_gemma":[0.9954953,0.0001023794,0.0001819121,0.003390884,0.0005560878,0.00009744102,0.00003701807,0.00003142884,0.0001075193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01637439,"threshold_uncertainty_score":0.8589891,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06103405796791655,"score_gpt":0.4050623304814818,"score_spread":0.3440282725135652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}