{"id":"W3094752049","doi":"10.1161/res.127.suppl_1.291","title":"Abstract 291: <i>In Vitro</i> Matured Human Embryonic Stem Cell-derived Cardiomyocytes Form Grafts With Enhanced Structure and Improved Electromechanical Integration in Injured Hearts","year":2020,"lang":"en","type":"article","venue":"Circulation Research","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Embryonic stem cell; Cell biology; Myocyte; Extracellular matrix; Transplantation; In vivo; Biology; Ex vivo; Sarcomere; Stem cell; In vitro; Polydimethylsiloxane; Medicine; Materials science; Gene; Internal medicine; Nanotechnology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001193605,0.0003627217,0.0001652528,0.0001782687,0.0001545553,0.0002750776,0.0001795538,0.0001988613,0.006979404],"category_scores_gemma":[0.00008370387,0.0001138038,0.0001764969,0.0001456748,0.0001673352,0.0001665101,0.0002094611,0.0004836632,0.002063175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002036766,"about_ca_system_score_gemma":0.0002286776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000370966,"about_ca_topic_score_gemma":0.00047573,"domain_scores_codex":[0.999891,0.000008966251,0.000009677785,0.00002220483,0.00005641614,0.00001169641],"domain_scores_gemma":[0.9999242,0.00001201243,0.00002064804,0.000008030795,0.00001620441,0.00001894816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000342859,0.0000110554,0.00008811887,0.00002029794,0.000001324579,0.00003381685,0.000004320313,0.00003693303,0.9987797,0.0000698755,0.0001737275,0.0007466226],"study_design_scores_gemma":[0.00001389209,0.0001213319,0.003364499,0.000007327583,0.000006900802,0.0002522783,0.00001501034,0.0006721021,0.9888721,0.00006961326,0.006601757,0.000003143248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9539111,0.002078986,0.01438461,0.0004998707,0.0004255221,0.0001432949,0.004552126,0.000405808,0.02359876],"genre_scores_gemma":[0.9476452,0.002752316,0.009890385,0.0002764484,0.000138773,0.0001799429,0.005730966,0.0002148592,0.03317101],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006979404,"threshold_uncertainty_score":0.02334845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02853612215072454,"score_gpt":0.3050333246280413,"score_spread":0.2764972024773168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}