{"id":"W3094752049","doi":"10.1161/res.127.suppl_1.291","title":"Abstract 291: <i>In Vitro</i> Matured Human Embryonic Stem Cell-derived Cardiomyocytes Form Grafts With Enhanced Structure and Improved Electromechanical Integration in Injured Hearts","year":2020,"lang":"en","type":"article","venue":"Circulation Research","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Embryonic stem cell; Cell biology; Myocyte; Extracellular matrix; Transplantation; In vivo; Biology; Ex vivo; Sarcomere; Stem cell; In vitro; Polydimethylsiloxane; Medicine; Materials science; Gene; Internal medicine; Nanotechnology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003406279,0.0001801909,0.0003914401,0.0002955687,0.00008379019,0.00003962003,0.00006312332,0.000172705,0.00001702069],"category_scores_gemma":[0.00005971357,0.0001382197,0.00003429833,0.0006888659,0.00007354009,0.0001026078,0.00002388651,0.0009488452,0.000001851652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001719468,"about_ca_system_score_gemma":0.0001058733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005893964,"about_ca_topic_score_gemma":0.0000759777,"domain_scores_codex":[0.9983702,0.00009797185,0.0002742364,0.0004182992,0.0004554868,0.0003837891],"domain_scores_gemma":[0.9993431,0.00006399778,0.00004660459,0.0001821768,0.0001663073,0.0001977904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004186091,0.00003190926,0.0004205708,0.0001798827,0.00001740978,0.00003172975,0.001257553,0.0002271916,0.9933691,0.00004524487,0.00002549592,0.003975284],"study_design_scores_gemma":[0.00361008,0.0005797515,0.1386546,0.0001996665,0.00001459183,0.00001735621,0.000453955,0.01014319,0.846075,0.00004374618,0.0000378258,0.0001701727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950302,0.001143594,0.001172997,0.001580425,0.00003602625,0.0009338143,0.000005576611,0.0000514782,0.00004589569],"genre_scores_gemma":[0.9992164,0.00002318465,0.0002625397,0.00003736546,0.000160719,0.0000477754,0.000127554,0.00003270389,0.00009179192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1472941,"threshold_uncertainty_score":0.5636435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02853612215072454,"score_gpt":0.3050333246280413,"score_spread":0.2764972024773168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}