{"id":"W3094872986","doi":"10.3390/cells9112388","title":"Protein Kinase C Alpha Cellular Distribution, Activity, and Proximity with Lamin A/C in Striated Muscle Laminopathies","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Heart and Stroke Foundation of Canada; Ottawa Hospital Research Institute; Canadian Institutes of Health Research; University of Ottawa","keywords":"Lamin; Cell biology; Alpha (finance); Chemistry; Biology; Nucleus; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005611217,0.0001110613,0.0001018548,0.0000114034,0.00004119004,0.00002198256,0.00005457945,0.0000991205,0.00001032992],"category_scores_gemma":[0.00002186245,0.00009525364,0.00001849891,0.0001006586,0.00005702645,0.00000738965,0.00005651129,0.00009804023,0.000004107137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008097334,"about_ca_system_score_gemma":0.00002623596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003431298,"about_ca_topic_score_gemma":0.00003789603,"domain_scores_codex":[0.9993915,0.00004529191,0.00008245189,0.0002728799,0.00006996565,0.0001379124],"domain_scores_gemma":[0.9997353,0.000002890492,0.00004320667,0.0001249929,0.00002895364,0.00006465586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001691708,0.00003262149,0.0005466416,0.00003524519,0.000008043639,0.00001176448,0.00006196489,0.000007258549,0.996503,0.00003286616,0.00016841,0.002422988],"study_design_scores_gemma":[0.0006983069,0.000449893,0.01635511,0.00001152213,0.00001020973,0.000001549614,0.00005566833,0.0001209079,0.9722677,0.00002327391,0.009860273,0.0001456098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998134,0.0000853431,0.001075844,0.0002235467,0.00002711684,0.0002957962,0.00003486016,0.00001421445,0.0001092387],"genre_scores_gemma":[0.9994529,0.00001550164,0.0001197676,0.00007244953,0.00008613433,0.00001154902,0.0001109623,0.00001272115,0.0001180144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02423535,"threshold_uncertainty_score":0.3884331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006372310599846592,"score_gpt":0.1813204152578586,"score_spread":0.174948104658012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}