{"id":"W3094912425","doi":"10.1503/jpn.200001","title":"Cortical inhibition, facilitation and plasticity in late-life depression: effects of venlafaxine pharmacotherapy","year":2021,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Transcranial Magnetic Stimulation Studies","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Krembil Foundation; University of Toronto; Centre for Addiction and Mental Health; University Health Network","funders":"National Institute of Mental Health; Weston Brain Institute; Canadian Institutes of Health Research; Ontario Ministry of Health and Long-Term Care; National Institutes of Health; Centre for Addiction and Mental Health; Fondation Brain Canada; Bristol-Myers Squibb; BrightFocus Foundation; Eli Lilly and Company; Ontario Ministry of Research and Innovation; Patient-Centered Outcomes Research Institute; Brain and Behavior Research Foundation","keywords":"Transcranial magnetic stimulation; Antidepressant; Neuroplasticity; Neuroscience; Psychology; Late life depression; Major depressive disorder; Venlafaxine; Depression (economics); Facilitation; Motor cortex; Prefrontal cortex; Medicine; Stimulation; Cognition; Hippocampus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001374929,0.0002133665,0.0003126039,0.0000728469,0.00006463959,0.0000947907,0.0001073603,0.0001035716,0.0004966065],"category_scores_gemma":[0.0002650971,0.00004058939,0.0001291153,0.00005138867,0.00009669126,0.00005041439,0.00006063457,0.000207219,0.00004946183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001112261,"about_ca_system_score_gemma":0.0001083444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003986373,"about_ca_topic_score_gemma":0.001417729,"domain_scores_codex":[0.9999425,0.00002514767,0.000005581311,0.000006831508,0.000008216751,0.00001163219],"domain_scores_gemma":[0.9999167,0.00002835118,0.00002446359,0.000006336963,0.000006665947,0.00001751865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.03865775,0.003428004,0.02040837,0.001280751,0.0007190628,0.0006722913,0.0001587709,0.001631062,0.4071398,0.0002279387,0.0005787403,0.5250975],"study_design_scores_gemma":[0.004881838,0.1175729,0.7876361,0.0002675791,0.0007062946,0.004493009,0.0001533019,0.003187501,0.07469031,0.0005099694,0.005862426,0.00003877499],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931158,0.005479787,0.0004072147,0.0000529396,0.00001285676,0.00005225945,0.00004079359,0.000010796,0.0008275581],"genre_scores_gemma":[0.9978643,0.001513486,0.0003164179,0.00003289762,0.00001090778,0.00002478575,0.00003036784,9.805879e-7,0.000205966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004966065,"threshold_uncertainty_score":0.001661301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02323668473360434,"score_gpt":0.2992255442036449,"score_spread":0.2759888594700405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}