{"id":"W3095134159","doi":"10.1182/blood-2020-135874","title":"Apollo: Phase 3 Randomized Study of Subcutaneous Daratumumab Plus Pomalidomide and Dexamethasone (D-Pd) Versus Pomalidomide and Dexamethasone (Pd) Alone in Patients (Pts) with Relapsed/Refractory Multiple Myeloma (RRMM)","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Pomalidomide; Daratumumab; Dexamethasone; Medicine; Internal medicine; Refractory (planetary science); Oncology; Multiple myeloma; Lenalidomide; Materials science","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007593951,0.0007053267,0.002469188,0.000417061,0.0001952961,0.00006329682,0.0002226906,0.0002415662,0.00006292481],"category_scores_gemma":[0.00349296,0.0005536451,0.0001678479,0.0006823151,0.000494854,0.000244158,0.0002468634,0.0007434619,0.00001235995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001499518,"about_ca_system_score_gemma":0.0002504709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001427112,"about_ca_topic_score_gemma":0.0006893988,"domain_scores_codex":[0.994779,0.001010951,0.001086939,0.001151219,0.001122793,0.0008491068],"domain_scores_gemma":[0.9949971,0.002643909,0.0004577324,0.0006743252,0.0002722418,0.0009546473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7845679,0.0144131,0.1786872,0.000303819,0.002717482,0.004298843,0.004665065,0.00001042571,0.003916136,0.000005278704,0.0000284031,0.006386295],"study_design_scores_gemma":[0.9300741,0.02372935,0.03631224,0.0002153117,0.001657054,0.0001745885,0.001638429,0.0009472689,0.004702173,0.000006370324,0.00003905197,0.0005040654],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917641,0.001908558,0.00003207254,0.0001670799,0.00008662938,0.005555429,0.0001235611,0.00009562652,0.0002669742],"genre_scores_gemma":[0.9964581,0.000259625,0.002523722,0.00008578671,0.00008559765,0.0002616485,0.0001421725,0.0001169512,0.00006641178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1455062,"threshold_uncertainty_score":0.9996915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02714099303185159,"score_gpt":0.2862342285527387,"score_spread":0.2590932355208871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}