{"id":"W3095291003","doi":"10.7554/elife.57246.sa2","title":"Author response: The HIV-1 latent reservoir is largely sensitive to circulating T cells","year":2020,"lang":"en","type":"peer-review","venue":"","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; AIDS Vancouver","funders":"","keywords":"Epitope; Antiretroviral therapy; CD8; Virology; Cytotoxic T cell; Immunology; Human immunodeficiency virus (HIV); Virus; Biology; T cell; Disease; Viral replication; Proteome; Viral load; Medicine; Immune system; Antibody; Genetics; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.003376633,0.0008357243,0.0008036447,0.0007494914,0.0008183147,0.003142581,0.001173898,0.002666361,0.3052645],"category_scores_gemma":[0.01354813,0.0004724332,0.0005960757,0.0007247753,0.0007069006,0.001802008,0.00148117,0.00177028,0.1276141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000805639,"about_ca_system_score_gemma":0.001492813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004603842,"about_ca_topic_score_gemma":0.0006590805,"domain_scores_codex":[0.9956529,0.001480564,0.0003413485,0.0009335665,0.001235235,0.0003564074],"domain_scores_gemma":[0.9908683,0.003281483,0.0006346066,0.0009991669,0.003463145,0.0007532259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001036147,0.00008823964,0.002528974,0.001209843,0.00004112182,0.0004074523,0.0001777424,0.0003076213,0.008456396,0.003091282,0.8643216,0.1183336],"study_design_scores_gemma":[0.0002249357,0.0002537568,0.00363067,0.0004305399,0.00002918566,0.0005835032,0.0004295488,0.00063422,0.007926253,0.003667854,0.9821377,0.00005186193],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.04595914,0.0127874,0.04127331,0.2130634,0.1700042,0.003247403,0.05105755,0.01072541,0.4518822],"genre_scores_gemma":[0.183676,0.00955251,0.0231809,0.08391783,0.02484585,0.002417205,0.02768669,0.003071125,0.6416519],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.3052645,"threshold_uncertainty_score":0.9909558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06706267580664588,"score_gpt":0.3424509851421388,"score_spread":0.275388309335493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}