{"id":"W3095307948","doi":"10.1007/s00213-020-05692-9","title":"Rapid and sustained decreases in suicidality following a single dose of ayahuasca among individuals with recurrent major depressive disorder: results from an open-label trial","year":2020,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Psychedelics and Drug Studies","field":"Psychology","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Toronto Metropolitan University","funders":"","keywords":"Ayahuasca; Major depressive disorder; Context (archaeology); Psychiatry; Depressive symptoms; Psychological intervention; Medicine; Intervention (counseling); Clinical psychology; Psychology; Anxiety; Mood","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005959854,0.0003790249,0.0009023287,0.0001638509,0.0001478334,0.00006223282,0.0006280135,0.0002008325,0.0001938708],"category_scores_gemma":[0.0003057228,0.0003350681,0.00006414854,0.0005089765,0.000275267,0.0002486968,0.0003250458,0.0003500038,0.000005606034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003544041,"about_ca_system_score_gemma":0.00007866853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002653126,"about_ca_topic_score_gemma":0.001518956,"domain_scores_codex":[0.9962966,0.0008460865,0.0009223512,0.001127598,0.0002372785,0.0005700445],"domain_scores_gemma":[0.9978069,0.0008398945,0.0005211766,0.0004038848,0.00009258821,0.0003355319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6280794,0.0182537,0.2452156,0.00009040049,0.003360955,0.0004746627,0.04116765,0.00001301262,0.006646205,0.000573253,0.01278527,0.04333997],"study_design_scores_gemma":[0.7466,0.01112491,0.2258619,0.0001122393,0.0007357286,0.000005329579,0.008227514,0.0001824843,0.000437122,0.00176309,0.003927634,0.001022042],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877129,0.003061556,0.00004278612,0.003099971,0.001007563,0.002044889,0.0003816107,0.00005504497,0.002593718],"genre_scores_gemma":[0.9975869,0.0001293032,0.0003971282,0.001032396,0.0002572861,0.0004045129,0.000120061,0.00004449332,0.00002793506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1185207,"threshold_uncertainty_score":0.9999101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06532019194352236,"score_gpt":0.388343473793752,"score_spread":0.3230232818502297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}