{"id":"W3095353694","doi":"10.1080/23723556.2020.1835423","title":"Bad to the bone: B cell acute lymphoblastic leukemia cells mediate bone destruction","year":2020,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Ontario Institute for Cancer Research; Hospital for Sick Children; Leukemia and Lymphoma Society of Canada","keywords":"RANKL; Activator (genetics); Effector; Cancer research; Medicine; Receptor; RANK Ligand; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002840047,0.0005719592,0.0004070173,0.000499135,0.0004545308,0.001322402,0.0002400022,0.00066917,0.00650557],"category_scores_gemma":[0.0002612254,0.0001537139,0.0002601505,0.0003182737,0.0006789151,0.0004949786,0.0008143294,0.001180784,0.001754235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003661681,"about_ca_system_score_gemma":0.0004175225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004307591,"about_ca_topic_score_gemma":0.0008045654,"domain_scores_codex":[0.9997537,0.0000526812,0.00001305078,0.00003169727,0.00008004688,0.00006879828],"domain_scores_gemma":[0.9998734,0.00001406656,0.00003274619,0.00001091287,0.00001857537,0.00005027688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001342619,0.000380158,0.01398356,0.002385038,0.0001696143,0.002048206,0.000451896,0.0005358481,0.7994389,0.01497592,0.02153819,0.14275],"study_design_scores_gemma":[0.0004906546,0.002423469,0.05889068,0.0004128082,0.0002834956,0.01123059,0.001522411,0.001001245,0.4157658,0.01085672,0.4970677,0.00005446843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5629297,0.352427,0.01380026,0.02055896,0.002749944,0.0002657666,0.001823674,0.0009160794,0.04452861],"genre_scores_gemma":[0.9300954,0.04817708,0.002089881,0.00330015,0.0005209111,0.00007122438,0.0006464544,0.00004147261,0.01505745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00650557,"threshold_uncertainty_score":0.02176332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009757562973587909,"score_gpt":0.2449300086098342,"score_spread":0.2351724456362463,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}