{"id":"W3095368690","doi":"10.1111/jth.15156","title":"Is there a role for the ACE2 receptor in SARS‐CoV‐2 interactions with platelets?","year":2020,"lang":"en","type":"review","venue":"Journal of Thrombosis and Haemostasis","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; Fonds de Recherche du Québec - Santé; Clinical Science Research and Development; National Institutes of Health; U.S. Department of Veterans Affairs; Canadian Institutes of Health Research; Health Services Research and Development","keywords":"Platelet; Receptor; Platelet activation; Protease-activated receptor; Transcriptome; Immunology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Biology; P2Y12; Cell biology; Gene; Medicine; Gene expression; Thrombin; Internal medicine; Platelet aggregation; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007477488,0.0003271785,0.002483105,0.0002059916,0.0001525351,0.00007505566,0.0002719225,0.0001506222,0.0001466719],"category_scores_gemma":[0.003447441,0.0001543033,0.000802036,0.000419676,0.0001715234,0.0001097922,0.0001603679,0.001232051,0.00001175948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002426111,"about_ca_system_score_gemma":0.0006574336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004733758,"about_ca_topic_score_gemma":0.00004853585,"domain_scores_codex":[0.9978546,0.0001272229,0.0009882649,0.000287617,0.0004584667,0.0002838169],"domain_scores_gemma":[0.991801,0.00670483,0.0007670271,0.0002698024,0.0002930186,0.0001643119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003805778,0.0001743565,0.000129104,0.007556396,0.003249611,0.00002846638,0.000511203,4.24585e-7,0.00000619938,0.00001233475,0.02521229,0.9627391],"study_design_scores_gemma":[0.001167118,0.001016265,0.0001808792,0.01843507,0.002454054,0.00003498103,0.0003471258,0.00002128789,0.00001924075,0.00003606785,0.9761398,0.0001480911],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001838838,0.9587643,0.00008814209,0.0394895,0.0001270766,0.001132824,0.0001363983,0.000006836211,0.00007106167],"genre_scores_gemma":[0.0003926542,0.9971166,0.0007178754,0.001186674,0.0003744148,0.00007421518,0.000004879294,0.0000489507,0.00008372204],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9625909,"threshold_uncertainty_score":0.6292304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2621535473562723,"score_gpt":0.5152325289169409,"score_spread":0.2530789815606686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}