{"id":"W3095395654","doi":"10.1016/j.sbi.2020.10.006","title":"Charting the complex composite nature of centrosomes, primary cilia and centriolar satellites","year":2020,"lang":"en","type":"review","venue":"Current Opinion in Structural Biology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Sinai Health System","funders":"Krembil Foundation; Canada First Research Excellence Fund; Canada Research Chairs; Ontario Research Foundation; Canada Foundation for Innovation; Canadian Cancer Society; Canadian Institutes of Health Research; Genome Canada","keywords":"Ciliopathies; Centrosome; Cilium; Biology; Centriole; Organelle; Cell biology; Neurodegeneration; Neuroscience; Microtubule; Genetics; Cell; Phenotype; Cell cycle; Gene; Medicine; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001095226,0.0003875221,0.0009833528,0.0000642647,0.00006895493,0.00001803547,0.0004095692,0.000543244,0.000008535555],"category_scores_gemma":[0.00005762341,0.0002517335,0.0002394824,0.0001523187,0.0002406454,0.000003101062,0.0004446082,0.0006535021,0.00000191513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003052491,"about_ca_system_score_gemma":0.00008869469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004415704,"about_ca_topic_score_gemma":0.000001435139,"domain_scores_codex":[0.99811,0.0003030711,0.0006525352,0.0005510065,0.00006953856,0.0003138808],"domain_scores_gemma":[0.9990627,0.00006655705,0.000453178,0.0003029041,0.00004844278,0.00006626819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003393657,0.00001477099,0.00165222,0.009069269,0.0001285399,3.790571e-7,0.00004249454,5.21293e-7,0.009645198,0.0008824853,0.0003351899,0.978195],"study_design_scores_gemma":[0.0002616534,0.00006889077,0.0005882194,0.001075235,0.00005254631,0.00003541881,0.000006995749,0.00001696658,0.0001201395,0.00005285822,0.9974605,0.0002605212],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002282006,0.9947566,0.00001150882,0.0000665734,0.001724381,0.0005914847,0.0005462763,0.000007170709,0.00001399572],"genre_scores_gemma":[0.001304927,0.9912314,0.0001323362,0.00004894226,0.0005713457,0.00001627377,0.006669591,0.00002267183,0.000002543232],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9971254,"threshold_uncertainty_score":0.9999935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03398738547005529,"score_gpt":0.3462713646934926,"score_spread":0.3122839792234373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}