{"id":"W3095532130","doi":"10.1016/j.cytogfr.2020.10.007","title":"Cytokines in oncolytic virotherapy","year":2020,"lang":"en","type":"review","venue":"Cytokine & Growth Factor Reviews","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Dalhousie University; University of Guelph","funders":"Labex Immuno-Oncology; High-end Foreign Experts Recruitment Plan of China; European Research Area Network on Cardiovascular Diseases; Chancellerie des Universités de Paris; Cancéropôle Ile de France; Institut National de la Santé et de la Recherche Médicale; Institut National Du Cancer; Institut Universitaire de France; Ligue Contre le Cancer; Fondation pour la Recherche Médicale; Seerave Foundation; Association pour la Recherche sur le Cancer; Fondation Leducq; Agence Nationale de la Recherche","keywords":"Oncolytic virus; Immunosurveillance; Virotherapy; Tumor microenvironment; Immune system; Cancer research; Cytotoxic T cell; Chemokine; Biology; Stromal cell; Antigen; Immunology; Immunotherapy; Lymphokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006696508,0.001196548,0.003722885,0.0003259621,0.00007543212,0.00008750655,0.001470467,0.0007329252,0.0003349907],"category_scores_gemma":[0.0004312197,0.000937461,0.001454356,0.0009414663,0.0001357643,0.00001009594,0.0003253825,0.000883109,0.0008380635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002306111,"about_ca_system_score_gemma":0.0006818285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001579596,"about_ca_topic_score_gemma":0.0001083871,"domain_scores_codex":[0.9943669,0.001162261,0.001729554,0.001480395,0.0004237384,0.000837161],"domain_scores_gemma":[0.9974909,0.0000705267,0.0006413916,0.001342005,0.00009174705,0.0003634651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002109819,0.0001155789,0.00006736408,0.008478508,0.0001644325,0.00005136851,0.00002087027,1.356612e-7,0.00255937,0.00001053941,0.002358743,0.9859621],"study_design_scores_gemma":[0.0007302543,0.001512922,0.00001294464,0.00331772,0.0001031558,0.00003467606,0.000001474627,9.695452e-7,0.001016436,0.00001128388,0.9923764,0.000881791],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002132386,0.995039,0.00003397534,0.00007660985,0.0002089006,0.003746853,0.000248662,0.00003901008,0.0003937678],"genre_scores_gemma":[0.00004922439,0.9957842,0.0001007709,0.0004706582,0.001220426,0.0009833992,0.0006612677,0.0002845416,0.0004455208],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9900177,"threshold_uncertainty_score":0.9999399,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07504463746088749,"score_gpt":0.3791220633045722,"score_spread":0.3040774258436847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}