{"id":"W3095532130","doi":"10.1016/j.cytogfr.2020.10.007","title":"Cytokines in oncolytic virotherapy","year":2020,"lang":"en","type":"review","venue":"Cytokine & Growth Factor Reviews","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Dalhousie University; University of Guelph","funders":"Labex Immuno-Oncology; High-end Foreign Experts Recruitment Plan of China; European Research Area Network on Cardiovascular Diseases; Chancellerie des Universités de Paris; Cancéropôle Ile de France; Institut National de la Santé et de la Recherche Médicale; Institut National Du Cancer; Institut Universitaire de France; Ligue Contre le Cancer; Fondation pour la Recherche Médicale; Seerave Foundation; Association pour la Recherche sur le Cancer; Fondation Leducq; Agence Nationale de la Recherche","keywords":"Oncolytic virus; Immunosurveillance; Virotherapy; Tumor microenvironment; Immune system; Cancer research; Cytotoxic T cell; Chemokine; Biology; Stromal cell; Antigen; Immunology; Immunotherapy; Lymphokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002949703,0.0005521768,0.0006449408,0.001248489,0.0001614726,0.0007948735,0.000424931,0.00072053,0.002786658],"category_scores_gemma":[0.00023596,0.0002132341,0.000299455,0.0009364046,0.0003364774,0.0007211493,0.0004584818,0.001748636,0.002268858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005214596,"about_ca_system_score_gemma":0.0005505552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000466647,"about_ca_topic_score_gemma":0.0007618258,"domain_scores_codex":[0.9998977,0.00001996731,0.00001045087,0.00001647059,0.00004131037,0.00001403916],"domain_scores_gemma":[0.9999217,0.00003672249,0.00001168894,0.000002840603,0.00001709725,0.000009975474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001251606,0.00009327295,0.0001143875,0.01022178,0.00004972205,0.0002383021,0.00008013478,0.000554271,0.01055088,0.01019608,0.02712638,0.9406496],"study_design_scores_gemma":[0.00001649175,0.0001037117,0.0002552666,0.001105178,0.00003289392,0.0007101842,0.00002223397,0.00008624961,0.001521092,0.001747793,0.9943901,0.000008937431],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002132411,0.9979352,0.0001758658,0.0001662232,0.0002435069,0.000005943853,0.00001382327,0.0000113615,0.001234889],"genre_scores_gemma":[0.001513615,0.9964362,0.0002350154,0.0001749057,0.0001834886,0.00001183181,0.00002973247,0.000002978501,0.001412092],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002786658,"threshold_uncertainty_score":0.009322345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07504463746088749,"score_gpt":0.3791220633045722,"score_spread":0.3040774258436847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}