{"id":"W3095617142","doi":"10.3389/fcell.2020.587691","title":"CEP164 Deficiency Causes Hyperproliferation of Pancreatic Cancer Cells","year":2020,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Daiichi Sankyo Foundation of Life Science; Japan Society for the Promotion of Science; Mochida Memorial Foundation for Medical and Pharmaceutical Research; York University; Kurata Memorial Hitachi Science and Technology Foundation; Takeda Science Foundation","keywords":"Ciliogenesis; Cilium; Cell biology; Biology; Centrosome; Cell cycle; Pancreatic cancer; Cyclin-dependent kinase 6; Cancer research; Cell growth; Cell; Cyclin-dependent kinase; Cancer; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003301508,0.0001052473,0.0001563168,0.00002946009,0.00002989299,0.000004112282,0.00007560592,0.0000905988,0.00002175977],"category_scores_gemma":[0.00002039795,0.00009451064,0.0000237844,0.00006866928,0.00009905885,0.000002134512,0.00006146581,0.00003355753,0.000002581397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008828015,"about_ca_system_score_gemma":0.0001287502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002642927,"about_ca_topic_score_gemma":0.000006697843,"domain_scores_codex":[0.9993521,0.00003341656,0.0001780869,0.0002487621,0.00003743717,0.0001502031],"domain_scores_gemma":[0.9997954,0.000004803636,0.00004482697,0.00004936097,0.00001817058,0.00008748358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007659543,0.00003133036,0.2017977,0.00004773564,0.00001196753,8.94218e-7,0.0001811147,0.00001209093,0.792586,0.000002818224,0.004341701,0.0009100807],"study_design_scores_gemma":[0.0006000263,0.0002134364,0.0141325,0.000008807721,0.00001735329,0.000001887144,0.0007031521,0.00006235737,0.9790337,0.00006926581,0.004977213,0.0001802765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918134,0.005701855,0.00125535,0.0000849073,0.0001671958,0.0001250297,0.00004565231,0.000004194769,0.0008024815],"genre_scores_gemma":[0.990909,0.001833954,0.006472544,0.0005742859,0.00003751882,0.0000192123,0.00007302153,0.000007018719,0.00007341308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1876652,"threshold_uncertainty_score":0.3854032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00805694414804103,"score_gpt":0.213520553386331,"score_spread":0.20546360923829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}