{"id":"W3095617142","doi":"10.3389/fcell.2020.587691","title":"CEP164 Deficiency Causes Hyperproliferation of Pancreatic Cancer Cells","year":2020,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Daiichi Sankyo Foundation of Life Science; Japan Society for the Promotion of Science; Mochida Memorial Foundation for Medical and Pharmaceutical Research; York University; Kurata Memorial Hitachi Science and Technology Foundation; Takeda Science Foundation","keywords":"Ciliogenesis; Cilium; Cell biology; Biology; Centrosome; Cell cycle; Pancreatic cancer; Cyclin-dependent kinase 6; Cancer research; Cell growth; Cell; Cyclin-dependent kinase; Cancer; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009346686,0.0004771429,0.0002777946,0.0003980469,0.0001861551,0.0003046113,0.000215991,0.0003628589,0.001618512],"category_scores_gemma":[0.0001476201,0.0002011411,0.0002756129,0.0002354216,0.0002254572,0.0001471091,0.0003060254,0.0006218333,0.0004506256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002570704,"about_ca_system_score_gemma":0.0002382022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005775355,"about_ca_topic_score_gemma":0.0005624083,"domain_scores_codex":[0.999828,0.00002465536,0.00003225658,0.00003980197,0.00004810035,0.00002705405],"domain_scores_gemma":[0.9997427,0.00004238977,0.00008045408,0.00002713789,0.00001314715,0.0000942278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001025713,0.00002063378,0.0002440675,0.00002919524,0.000005464227,0.0004751151,0.000009655255,0.00005925615,0.9981467,0.00005585825,0.00004257889,0.0008089881],"study_design_scores_gemma":[0.00003387416,0.0003740212,0.01111793,0.0000103103,0.00003332266,0.002946978,0.00005172349,0.001345404,0.9802487,0.00007762928,0.00374902,0.00001103702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941078,0.0009853935,0.002126454,0.0001078664,0.00006456024,0.00004242557,0.001001016,0.0002327641,0.001331638],"genre_scores_gemma":[0.9937174,0.0008974709,0.001802845,0.00004132167,0.00001293471,0.00004959504,0.0008611581,0.00004533125,0.00257194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001618512,"threshold_uncertainty_score":0.005414426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00805694414804103,"score_gpt":0.213520553386331,"score_spread":0.20546360923829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}