{"id":"W3095643285","doi":"","title":"Compartmental targeting for Foscan based photodynamic treatment in vivo: correlation between efficiency, pharmacokinetics and regional distribution of apoptosis","year":2009,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre d'expertise et de recherche en infrastructures urbaines","funders":"","keywords":"Photodynamic therapy; Photosensitizer; Apoptosis; Pharmacokinetics; In vivo; Distribution (mathematics); Necrosis; Cancer research; Chemistry; Immunohistochemistry; Reactive oxygen species; Pathology; Caspase 3; Pharmacology; Programmed cell death; Medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004180277,0.0003742645,0.0004838698,0.0003279962,0.0002395486,0.0006273713,0.0003417818,0.0003608674,0.0017936],"category_scores_gemma":[0.0007375245,0.000257509,0.0002230005,0.0004215958,0.0004548973,0.0006901228,0.0001921196,0.0005617108,0.0003313639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00129934,"about_ca_system_score_gemma":0.0009267644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004595833,"about_ca_topic_score_gemma":0.003007373,"domain_scores_codex":[0.9997812,0.00005297511,0.000007222511,0.00005702304,0.00005343476,0.0000481754],"domain_scores_gemma":[0.9997253,0.0001100825,0.00006616904,0.00003472749,0.00004078376,0.00002302591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002268581,0.00008452756,0.0007116394,0.00009569956,0.0000210871,0.00003924536,0.00008803401,0.001067374,0.98594,0.0002979436,0.0001052697,0.009280735],"study_design_scores_gemma":[0.00002048238,0.0005884588,0.003577674,0.000004733676,0.00004112891,0.0001669371,0.00004030476,0.004219094,0.9903957,0.0001120456,0.0008204891,0.00001300413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9782563,0.003691561,0.01598751,0.00008200948,0.00001693301,0.00006044325,0.0002685021,0.0001608308,0.001475865],"genre_scores_gemma":[0.9933671,0.0008221981,0.003237316,0.00002015741,0.000007092895,0.00004932186,0.0001642954,0.00007109111,0.002261408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004595833,"threshold_uncertainty_score":0.009427369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02174155122072167,"score_gpt":0.2980960189419931,"score_spread":0.2763544677212714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}