{"id":"W3095668396","doi":"10.1212/wnl.94.15_supplement.2669","title":"A Role for Dysfunctional RNA Binding Proteins in the Pathogenesis of Neurodegeneration in MS (2669)","year":2020,"lang":"en","type":"article","venue":"Neurology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Neurodegeneration; Dysfunctional family; Pathogenesis; Neuroscience; RNA-binding protein; Medicine; Chemistry; RNA; Biology; Biochemistry; Immunology; Disease; Pathology; Psychiatry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005927314,0.0002587033,0.0001670765,0.0002798471,0.0002315157,0.0003469506,0.0002550794,0.0005214551,0.005367813],"category_scores_gemma":[0.0002272255,0.00009355452,0.0001949795,0.0001589504,0.0002330709,0.0002147675,0.0001923219,0.0006085261,0.001597042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002155121,"about_ca_system_score_gemma":0.0001757208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008105731,"about_ca_topic_score_gemma":0.001295204,"domain_scores_codex":[0.9999005,0.00002146717,0.000007489203,0.00001610205,0.00003023946,0.0000241276],"domain_scores_gemma":[0.9998804,0.00002587697,0.00002184555,0.00001197218,0.00002128641,0.00003858692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007414056,0.0001769599,0.003160974,0.0001105642,0.00001835166,0.0006678959,0.00004199231,0.0002421714,0.9803739,0.002508044,0.001638741,0.0103191],"study_design_scores_gemma":[0.00008934042,0.001494107,0.04175225,0.00006880261,0.00006975498,0.004111792,0.0001934913,0.002892792,0.9126827,0.003310615,0.03331257,0.00002176379],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9460443,0.0128998,0.01628593,0.003247123,0.0005507568,0.00009461633,0.001878941,0.000230727,0.01876777],"genre_scores_gemma":[0.958021,0.004763416,0.01064312,0.001163949,0.00009293146,0.00006060941,0.001334407,0.00003167982,0.02388896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005367813,"threshold_uncertainty_score":0.01795715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01890164129166848,"score_gpt":0.2504885717750391,"score_spread":0.2315869304833706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}