{"id":"W3095704533","doi":"10.1182/blood-2020-137078","title":"Polatuzumab Vedotin Plus Bendamustine and Rituximab in Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Updated Results of a Phase Ib/II Randomized Study and Preliminary Results of a Single-Arm Extension","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada); McGill University; Jewish General Hospital; BC Cancer Agency","funders":"","keywords":"Bendamustine; Rituximab; Medicine; Refractory (planetary science); Diffuse large B-cell lymphoma; Phases of clinical research; Lymphoma; Internal medicine; Oncology; Chemotherapy; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005180883,0.00083031,0.002035494,0.0004208357,0.0002079501,0.001391105,0.0009004127,0.0008452144,0.002412158],"category_scores_gemma":[0.003263147,0.000488083,0.001881827,0.0006849894,0.0006258946,0.001010879,0.0004583118,0.002335168,0.0003244829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008643603,"about_ca_system_score_gemma":0.001336382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007114965,"about_ca_topic_score_gemma":0.002176804,"domain_scores_codex":[0.9980456,0.001223916,0.0001837096,0.0002088643,0.0002002557,0.0001376578],"domain_scores_gemma":[0.9972423,0.0008487696,0.0008536977,0.0002486332,0.0002640127,0.0005425509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8356913,0.01008972,0.007603527,0.002175676,0.00617211,0.0001781307,0.0001856797,0.001144234,0.01255686,0.000290096,0.002874763,0.1210379],"study_design_scores_gemma":[0.8421325,0.1264874,0.01574693,0.0002268395,0.00656806,0.0003355934,0.00006462447,0.0007400958,0.0017333,0.0002690812,0.005656193,0.00003955836],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722692,0.0172726,0.001226728,0.001155961,0.0003222709,0.002910202,0.002331668,0.0001247821,0.002386575],"genre_scores_gemma":[0.9784631,0.008411984,0.002928968,0.002009769,0.0005128153,0.002376554,0.004148066,0.00004496778,0.001103763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005180883,"threshold_uncertainty_score":0.02739942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03275574278423302,"score_gpt":0.3085714796981534,"score_spread":0.2758157369139204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}