{"id":"W3095704533","doi":"10.1182/blood-2020-137078","title":"Polatuzumab Vedotin Plus Bendamustine and Rituximab in Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Updated Results of a Phase Ib/II Randomized Study and Preliminary Results of a Single-Arm Extension","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada); McGill University; Jewish General Hospital; BC Cancer Agency","funders":"","keywords":"Bendamustine; Rituximab; Medicine; Refractory (planetary science); Diffuse large B-cell lymphoma; Phases of clinical research; Lymphoma; Internal medicine; Oncology; Chemotherapy; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00167593,0.0003529075,0.001684118,0.000364996,0.00008534535,0.00001570532,0.0001769908,0.0002136311,0.00001216579],"category_scores_gemma":[0.003924275,0.0003029447,0.0001156814,0.0006571569,0.0002967851,0.00008946628,0.0004625149,0.0004351054,0.00000244286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000942897,"about_ca_system_score_gemma":0.0004123895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005168617,"about_ca_topic_score_gemma":0.00006207671,"domain_scores_codex":[0.9957632,0.0006199306,0.001507376,0.0008653608,0.0007565656,0.0004875046],"domain_scores_gemma":[0.9973947,0.0007874785,0.0004975043,0.0006414915,0.0002931041,0.0003857363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7339652,0.1704149,0.0002390691,0.0007414269,0.0002247105,0.001056399,0.01500877,0.000001357764,0.07554425,0.000003264755,0.000681105,0.002119609],"study_design_scores_gemma":[0.9492881,0.02394792,0.001040131,0.0005847712,0.0006409735,0.00005490387,0.001688234,0.00291967,0.01919079,0.000007930001,0.0003999663,0.000236632],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911311,0.004305256,0.000005370207,0.0007883028,0.00005128518,0.002815166,0.0003849901,0.00006232794,0.0004561844],"genre_scores_gemma":[0.9986539,0.000344075,0.0004311509,0.0001008931,0.00008007637,0.00004919682,0.0001449356,0.00006360013,0.00013216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2153229,"threshold_uncertainty_score":0.9999422,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03275574278423302,"score_gpt":0.3085714796981534,"score_spread":0.2758157369139204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}