{"id":"W3095738174","doi":"10.1182/blood-2020-142737","title":"Plasmacytoid Dendritic Cells Surveil Megakaryocyte Sialic Acid to Regulate Thrombopoiesis","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Thrombopoiesis; Antigen; Immune system; Biology; Immunology; Sialic acid; Megakaryocyte; Cell biology; Stem cell; Haematopoiesis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002054482,0.0001804079,0.0002025073,0.0002171966,0.0002048934,0.0005322671,0.0001734039,0.0003086289,0.001542202],"category_scores_gemma":[0.0002934086,0.0001176182,0.0001891612,0.0001319488,0.0002173543,0.0003271991,0.0003925899,0.0005993773,0.0006662288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002609852,"about_ca_system_score_gemma":0.0003245587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002792866,"about_ca_topic_score_gemma":0.0004237864,"domain_scores_codex":[0.9998537,0.00002396735,0.00001260658,0.00002920905,0.00003238736,0.00004806802],"domain_scores_gemma":[0.9998611,0.00001086086,0.0000250651,0.00001176262,0.00004246273,0.0000487482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004646031,0.00005108039,0.01052069,0.0004434293,0.00005421356,0.00116256,0.0003321095,0.0003025601,0.9284322,0.0053072,0.004160847,0.04876839],"study_design_scores_gemma":[0.0004400931,0.001182293,0.1012596,0.0003213752,0.0002897978,0.004107707,0.001533213,0.005615268,0.556981,0.009618932,0.3185796,0.00007101361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.890592,0.05873838,0.01782808,0.003281846,0.001357471,0.0001910176,0.001243073,0.000472299,0.0262958],"genre_scores_gemma":[0.9781481,0.009604647,0.00273939,0.000709287,0.0002556073,0.0000528607,0.0003902753,0.00004095118,0.008058889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001542202,"threshold_uncertainty_score":0.005159199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01906094357797162,"score_gpt":0.2434740390304915,"score_spread":0.2244130954525199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}