{"id":"W3095758083","doi":"10.1182/blood-2020-139281","title":"Long-Term Effect of Ruxolitinib (RUX) in Inadequately Controlled Polycythemia Vera (PV) without Splenomegaly: 5-Year Results from the Phase 3 Response-2 Study","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Ruxolitinib; Internal medicine; Polycythemia vera; Randomization; Phlebotomy; Gastroenterology; Myelofibrosis; Randomized controlled trial; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003493979,0.0007204621,0.002082869,0.0002806479,0.0003723204,0.001016507,0.0005231019,0.001030343,0.001513793],"category_scores_gemma":[0.001353077,0.0002491745,0.002216595,0.0002732119,0.0005268729,0.0008732491,0.0003443955,0.002449838,0.000445811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004509275,"about_ca_system_score_gemma":0.0005881618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004976246,"about_ca_topic_score_gemma":0.001126215,"domain_scores_codex":[0.9992379,0.0004026321,0.00005876227,0.00009834101,0.00006669677,0.0001357044],"domain_scores_gemma":[0.9985843,0.000347815,0.0004278543,0.000134852,0.00008981812,0.0004153421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8084936,0.04011908,0.01185279,0.0007696646,0.002634042,0.0002897586,0.0001994833,0.002023652,0.01789458,0.0001363418,0.002354291,0.1132327],"study_design_scores_gemma":[0.2091877,0.7320448,0.0501539,0.00009551615,0.001772387,0.0003848255,0.00009346444,0.001415954,0.002776682,0.0001862192,0.001840529,0.00004800312],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926318,0.00492472,0.0003649416,0.0002010891,0.00007585076,0.0003335076,0.0007509867,0.00004801486,0.0006690517],"genre_scores_gemma":[0.9954187,0.001475788,0.0003856467,0.0004714832,0.0001174332,0.0003065029,0.001019225,0.00001230033,0.000792852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003493979,"threshold_uncertainty_score":0.01847816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0271808942966599,"score_gpt":0.3156119923488506,"score_spread":0.2884310980521907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}