{"id":"W3096049589","doi":"10.1182/blood-2020-141029","title":"Daratumumab (DARA) Plus Carfilzomib, Pomalidomide, Dexamethasone (KPd) in Lenalidomide Refractory Multiple Myeloma (MM): A Multi-Center MMRC Study","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Daratumumab; Pomalidomide; Carfilzomib; Medicine; Lenalidomide; Internal medicine; Cohort; Population; Refractory (planetary science); Regimen; Oncology; Dexamethasone; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004112614,0.001665768,0.002203941,0.0006427103,0.0006923846,0.001251412,0.00111866,0.001189928,0.002286224],"category_scores_gemma":[0.001136231,0.0009189939,0.00222165,0.0006955317,0.00080311,0.001177981,0.0006523426,0.003339017,0.0009246221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001220218,"about_ca_system_score_gemma":0.001855201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001457913,"about_ca_topic_score_gemma":0.002656323,"domain_scores_codex":[0.9987385,0.0006300792,0.00009395027,0.0002190994,0.0001497563,0.000168604],"domain_scores_gemma":[0.9984331,0.0001724239,0.000313932,0.0001630638,0.0001262742,0.0007911729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7254159,0.1385023,0.02334233,0.0008748728,0.004111148,0.0003703904,0.0004521314,0.001443217,0.03584959,0.0001422355,0.002130125,0.06736575],"study_design_scores_gemma":[0.4044182,0.5394545,0.04755026,0.00005156083,0.00205402,0.0004783352,0.00009945275,0.0007292636,0.002685726,0.00007171091,0.002357547,0.00004950859],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963418,0.001453063,0.0001420032,0.0002212606,0.00004332765,0.0009461661,0.0003738061,0.00002847503,0.0004500242],"genre_scores_gemma":[0.9949805,0.001206706,0.0008087555,0.0004335848,0.0002245912,0.0007689899,0.0007735926,0.00001432943,0.0007888892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004112614,"threshold_uncertainty_score":0.02174985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06429584796946747,"score_gpt":0.3207606016718996,"score_spread":0.2564647537024322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}