{"id":"W3096084910","doi":"10.3390/biomedicines8110469","title":"Dietary Vitamin B6 Deficiency Impairs Gut Microbiota and Host and Microbial Metabolites in Rats","year":2020,"lang":"en","type":"article","venue":"Biomedicines","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Children's Hospital Research Institute; Alberta Innovates","keywords":"Gut flora; Lachnospiraceae; Biology; Bacteroides; Metabolomics; Butyrate; Cecum; Metabolite; Vitamin; Metabolism; Dysbiosis; Internal medicine; Endocrinology; Firmicutes; Microbiology; Biochemistry; Bacteria; Medicine; Fermentation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002302207,0.000611012,0.0006016882,0.001034319,0.000374071,0.0003658496,0.0002460965,0.0005033574,0.001748402],"category_scores_gemma":[0.0002043599,0.0004060208,0.0003735792,0.0003442742,0.0005468477,0.0003561188,0.0004263743,0.001037262,0.0003905422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003824631,"about_ca_system_score_gemma":0.0004701949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002767996,"about_ca_topic_score_gemma":0.003734222,"domain_scores_codex":[0.9996635,0.00004479383,0.00002724194,0.00009305347,0.00007743319,0.00009391281],"domain_scores_gemma":[0.9995126,0.00002347098,0.0001278246,0.00004510804,0.00004833012,0.0002425987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009158706,0.0008751575,0.005828786,0.00006455382,0.0000424178,0.0001586216,0.0001037827,0.00006784443,0.9796283,0.00007165239,0.00009272199,0.003907478],"study_design_scores_gemma":[0.00041626,0.01655993,0.1745699,0.00005572998,0.0002938819,0.001066695,0.001334833,0.001883467,0.7997439,0.0004460538,0.003539908,0.00008942725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984967,0.000452385,0.0004001955,0.00006972536,0.00001789154,0.00001079632,0.0002562893,0.00003191654,0.0002642886],"genre_scores_gemma":[0.9939556,0.0006382032,0.0009749983,0.0001112856,0.000009523284,0.00005141664,0.0004647443,0.00002763433,0.003766667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002767996,"threshold_uncertainty_score":0.005849004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0118198858354696,"score_gpt":0.2476319498762515,"score_spread":0.2358120640407819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}