{"id":"W3096175189","doi":"10.1016/j.heliyon.2020.e05330","title":"AU richness within the 5′ coding region of the Escherichia coli heat-stable enterotoxin b mRNA affects toxin secretion","year":2020,"lang":"en","type":"article","venue":"Heliyon","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Laurentian University","funders":"Laurentian University","keywords":"Secretion; Coding region; Messenger RNA; Species richness; Biology; Escherichia coli; Signal peptide; Gene; Secretory protein; Enterotoxin; Molecular biology; Genetics; Biochemistry; Peptide sequence; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002168605,0.0001400751,0.0001419243,0.00001067097,0.0001577666,0.00002230844,0.0003029988,0.0001315485,0.00001256326],"category_scores_gemma":[0.0001374974,0.00008787773,0.0001028786,0.0001441192,0.00006270486,0.000005145695,0.0001337876,0.0001065798,0.000005881153],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001760913,"about_ca_system_score_gemma":0.00006950078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002410363,"about_ca_topic_score_gemma":0.00002564495,"domain_scores_codex":[0.9989841,0.0002474324,0.0001733619,0.0002462949,0.000166665,0.0001821312],"domain_scores_gemma":[0.9994038,0.00002111818,0.0001285312,0.0003485563,0.00003930997,0.00005868318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001215345,0.00001802016,0.0009635441,0.0001341407,0.00002086678,0.000001349013,0.0003764821,0.0000854579,0.9975443,0.0003881594,0.0001895559,0.0001565183],"study_design_scores_gemma":[0.0002405523,0.000205371,0.0006676348,0.0001432909,0.00001921334,0.000005716568,0.0002591175,0.0001439865,0.9948925,0.0000358613,0.003276865,0.0001098473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990643,0.0008915425,0.005403978,0.001391002,0.0002634584,0.0005912785,0.00000631499,0.00001478809,0.0007946834],"genre_scores_gemma":[0.9982029,0.0001545737,0.0001593008,0.0009433012,0.0002178267,0.00005725037,0.000008345577,0.00002142283,0.0002351434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007559882,"threshold_uncertainty_score":0.358355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01654965864699696,"score_gpt":0.2237219040366478,"score_spread":0.2071722453896508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}