{"id":"W3096186999","doi":"10.7759/cureus.11224","title":"Immunotherapy Benefit in a Patient With Non-Small Cell Lung Cancer and a Rare BRAF Mutation","year":2020,"lang":"en","type":"article","venue":"Cureus","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba; University of Manitoba; Research Institute in Oncology and Hematology; University of Winnipeg","funders":"Canadian Institutes of Health Research; CancerCare Manitoba Foundation; GlaxoSmithKline; Manitoba Medical Service Foundation; Pfizer; AstraZeneca; Horizon 2020 Framework Programme; Eli Lilly and Company","keywords":"Medicine; Anaplastic lymphoma kinase; Nivolumab; Immunotherapy; Lung cancer; Oncology; Mutation; Epidermal growth factor receptor; Cancer research; Internal medicine; Chemotherapy; Targeted therapy; Cancer; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001313887,0.0003405584,0.0005286892,0.0005389708,0.001138861,0.0005675688,0.0002676568,0.002520456,0.002620446],"category_scores_gemma":[0.000781858,0.0001743107,0.000561835,0.0002553293,0.0004506233,0.0006335651,0.000303807,0.00136809,0.0007973793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006329402,"about_ca_system_score_gemma":0.0004902999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007634,"about_ca_topic_score_gemma":0.002173868,"domain_scores_codex":[0.9999044,0.00001588567,0.000009188662,0.00001753097,0.00001346218,0.00003949826],"domain_scores_gemma":[0.9997541,0.00007100921,0.00003330275,0.00001041218,0.00001236347,0.0001187874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001761004,0.0001086255,0.01717616,0.00005998708,0.00001131249,0.9692756,0.0001573604,0.0001101726,0.002357741,0.0004180163,0.001740334,0.0084086],"study_design_scores_gemma":[0.00002110535,0.0002508335,0.007883934,0.00002703679,0.00001456703,0.987186,0.0001189868,0.0003444413,0.0006898144,0.0004441316,0.003011373,0.000007778521],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9413258,0.009342327,0.001437762,0.01697845,0.000601844,0.0001179906,0.0001851998,0.0001375031,0.02987314],"genre_scores_gemma":[0.9927329,0.001520658,0.0007163644,0.001999309,0.0005550223,0.00001275219,0.00006625082,0.00001307064,0.002383679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002620446,"threshold_uncertainty_score":0.008766294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008914664854851305,"score_gpt":0.2721151826229476,"score_spread":0.2632005177680963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}