{"id":"W3096252915","doi":"10.1002/acr2.11185","title":"Adjunctive Treatment With Avacopan, an Oral C5a Receptor Inhibitor, in Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis","year":2020,"lang":"en","type":"article","venue":"ACR Open Rheumatology","topic":"Vasculitis and related conditions","field":"Medicine","cited_by":121,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Medicine; Anti-neutrophil cytoplasmic antibody; Vasculitis; Internal medicine; Adverse effect; Cyclophosphamide; Placebo; Population; Gastroenterology; Chemotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001126854,0.0006114906,0.002007408,0.0002274663,0.0002328899,0.0004187106,0.0003605629,0.0004931481,0.001090427],"category_scores_gemma":[0.0009881731,0.0002467513,0.0007974678,0.0002159572,0.0003800999,0.0003448649,0.0002213431,0.001179127,0.0001623212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003087464,"about_ca_system_score_gemma":0.0004930884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003059317,"about_ca_topic_score_gemma":0.001153554,"domain_scores_codex":[0.9993852,0.0003367008,0.00005228117,0.00008116873,0.00007821554,0.00006631296],"domain_scores_gemma":[0.9994185,0.0001891269,0.000143653,0.00003424855,0.00003693734,0.0001774754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7125381,0.01934391,0.0164489,0.001591289,0.002263358,0.0005617851,0.0001511814,0.001918929,0.0339694,0.000178571,0.0008956649,0.2101389],"study_design_scores_gemma":[0.2767651,0.6680205,0.04265474,0.0001225177,0.001467326,0.000756098,0.00007263045,0.002280136,0.004939176,0.0001530463,0.002741814,0.00002679217],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943824,0.004271591,0.0002076807,0.00009590205,0.0001111749,0.0001868739,0.00006007874,0.00001615815,0.0006680632],"genre_scores_gemma":[0.9976885,0.001151355,0.0003935824,0.0001364888,0.0002002169,0.0001333957,0.00008189833,0.000001735793,0.0002129149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002007408,"threshold_uncertainty_score":0.005959451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01359030263685443,"score_gpt":0.2600942753311569,"score_spread":0.2465039726943025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}