{"id":"W3096309541","doi":"10.1182/blood-2020-139416","title":"Effect of Pembrolizumab Monotherapy Versus Brentuximab Vedotin (BV) on Symptoms Associated with Health-Related Quality of Life (HRQoL) in Relapsed/Refractory (R/R) Classical Hodgkin Lymphoma (cHL) in the Randomized, Phase 3, Keynote-204 Study","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Jewish General Hospital","funders":"","keywords":"Brentuximab vedotin; Classical Hodgkin lymphoma; Pembrolizumab; Medicine; Internal medicine; Oncology; Refractory (planetary science); Quality of life (healthcare); Lymphoma; Randomized controlled trial; Hodgkin lymphoma; Cancer; Immunotherapy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001972416,0.0009840651,0.001492157,0.0002406213,0.000316426,0.0007923854,0.0007451927,0.0008889104,0.003544632],"category_scores_gemma":[0.001277818,0.0004521275,0.00165361,0.0002300086,0.0005842853,0.0007872461,0.0003867454,0.002265885,0.0005374579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007793954,"about_ca_system_score_gemma":0.001014602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006389779,"about_ca_topic_score_gemma":0.002077945,"domain_scores_codex":[0.9994767,0.0003069636,0.00003835397,0.00007300314,0.00003362386,0.00007138728],"domain_scores_gemma":[0.9992046,0.0002062192,0.0002220602,0.00005733047,0.00003950081,0.0002702982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9705865,0.008110894,0.001723158,0.0004944571,0.001151809,0.00003795774,0.00003872858,0.0005094374,0.003969119,0.000052358,0.0006395352,0.01268611],"study_design_scores_gemma":[0.7837611,0.2036222,0.008567506,0.00005997762,0.001433701,0.00007764812,0.00003840566,0.0006717165,0.000970093,0.0001348702,0.0006446941,0.00001812723],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950748,0.001790244,0.0001690936,0.0002583473,0.0001361602,0.000898241,0.0007064165,0.00003387173,0.0009327117],"genre_scores_gemma":[0.9960788,0.0007860792,0.0004078559,0.0003634086,0.0001094981,0.0008962241,0.0006090556,0.00000640705,0.0007427706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003544632,"threshold_uncertainty_score":0.01185799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02919750974067392,"score_gpt":0.3203198412755852,"score_spread":0.2911223315349112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}