{"id":"W3096340533","doi":"10.3389/fgene.2020.558762","title":"Association of the Lactase Persistence Haplotype Block With Disease Risk in Populations of European Descent","year":2020,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; National Institute for Health and Care Research; European Commission; Royal Marsden NHS Foundation Trust; National Cancer Research Institute; Cancer Research Institute; California Dairy Research Foundation; U.S. Department of Agriculture","keywords":"Haplotype; Lactase; Lactose intolerance; Biology; Genetics; Single-nucleotide polymorphism; Allele; Disease; Gene; Genotype; Lactose; Internal medicine; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001441351,0.0002421836,0.0004559009,0.0006801322,0.0003520385,0.0005193583,0.0002556286,0.0003842214,0.002272213],"category_scores_gemma":[0.00227134,0.0002083077,0.0008908211,0.0009984319,0.0003957078,0.0002768317,0.0004021686,0.0003291903,0.0001138628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001317103,"about_ca_system_score_gemma":0.0002081104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003459422,"about_ca_topic_score_gemma":0.005067897,"domain_scores_codex":[0.9990158,0.0003903073,0.00006954248,0.000388817,0.00005892647,0.00007658578],"domain_scores_gemma":[0.9984736,0.0007362783,0.0003956146,0.0002212565,0.000054328,0.0001190063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001229963,0.00002054121,0.9828257,0.00006591058,0.002604479,0.0002353598,0.0001757915,0.0004360576,0.006311577,0.0002842441,0.0001388602,0.005671664],"study_design_scores_gemma":[0.0000351935,0.0001369208,0.9966033,0.00001683846,0.0007574587,0.0003103579,0.00008541381,0.0009466799,0.0003999847,0.0003420486,0.000358704,0.000007106277],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969003,0.0009427864,0.001339865,0.00006326767,0.000008776324,0.000005577113,0.0003782078,0.00001298656,0.0003481741],"genre_scores_gemma":[0.9990724,0.000162463,0.0003773296,0.00001398506,0.000007680602,0.00000645515,0.0002573481,0.000004912857,0.00009739966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003459422,"threshold_uncertainty_score":0.007622659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01399388620705838,"score_gpt":0.2175191677664041,"score_spread":0.2035252815593458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}