{"id":"W3096378490","doi":"10.1182/blood-2020-139785","title":"DREAMM-8: A Phase III Study of the Efficacy and Safety of Belantamab Mafodotin with Pomalidomide and Dexamethasone (B-Pd) Vs Pomalidomide Plus Bortezomib and Dexamethasone (PVd) in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Pomalidomide; Medicine; Lenalidomide; Dexamethasone; Bortezomib; Internal medicine; Multiple myeloma; Refractory (planetary science); Oncology; Phases of clinical research; Surgery; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002770971,0.0016611,0.0024853,0.0005016706,0.0004423798,0.001231088,0.001726954,0.00160778,0.004395511],"category_scores_gemma":[0.0009876009,0.0008897036,0.002170657,0.0004980668,0.001093813,0.001076381,0.0007110087,0.005049914,0.001506628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001971401,"about_ca_system_score_gemma":0.002054677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001258308,"about_ca_topic_score_gemma":0.003613063,"domain_scores_codex":[0.9992535,0.0003642308,0.00003987474,0.0001332785,0.0000862056,0.0001228608],"domain_scores_gemma":[0.9991432,0.0001066906,0.0001671636,0.00007669555,0.0000523675,0.0004538433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7706133,0.0875264,0.003833624,0.001074323,0.001909699,0.0001781513,0.0003499455,0.002483063,0.03398057,0.0005378374,0.005911605,0.09160154],"study_design_scores_gemma":[0.6049224,0.3809148,0.005351069,0.00003891617,0.0005056735,0.0002918535,0.00006602936,0.001093726,0.002705607,0.0002896643,0.003777971,0.00004231375],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843461,0.004805639,0.0008168475,0.001025108,0.0003037376,0.003031714,0.00271649,0.0002238092,0.002730642],"genre_scores_gemma":[0.9763747,0.002552119,0.004553794,0.001542934,0.0002456296,0.004343098,0.005692661,0.00006969574,0.004625472],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004395511,"threshold_uncertainty_score":0.01470447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0162206136942956,"score_gpt":0.2578425558123262,"score_spread":0.2416219421180306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}