{"id":"W3096464204","doi":"10.3389/fcell.2020.571677","title":"Epidermal Growth Factor Is Essential for the Maintenance of Novel Prostate Epithelial Cells Isolated From Patient-Derived Organoids","year":2020,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Faculty of Medicine, American University of Beirut; York University; New York University Abu Dhabi; American University of Beirut","keywords":"Organoid; Biology; Prostate cancer; Epidermal growth factor; Cancer research; Transcriptome; Cell culture; Prostate; Cell growth; Cell biology; Computational biology; Cancer; Gene expression; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002263528,0.0002008262,0.0002657061,0.0002105813,0.0002305432,0.0005792599,0.0002429288,0.0002312346,0.001198805],"category_scores_gemma":[0.0002967895,0.0001605192,0.0003282095,0.0002479458,0.0001898837,0.0002240486,0.0003899552,0.0007870638,0.0008683099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001945292,"about_ca_system_score_gemma":0.0002562812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000995873,"about_ca_topic_score_gemma":0.001399938,"domain_scores_codex":[0.9996853,0.00004952378,0.00003448677,0.00007692268,0.0001107325,0.00004316033],"domain_scores_gemma":[0.9997995,0.00003050504,0.00002621989,0.00005218586,0.00003779446,0.00005382676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004934478,0.00001300373,0.0004000755,0.00003200602,0.000006407073,0.0001246839,0.00004871096,0.00004947757,0.9974266,0.00008199826,0.0001166102,0.001651131],"study_design_scores_gemma":[0.00001215554,0.0001708144,0.01081703,0.00001435715,0.00002670588,0.001657999,0.0001261367,0.001239702,0.9706175,0.00007233785,0.01523239,0.00001293681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9524224,0.003706061,0.03492878,0.0003950347,0.0001168909,0.000262822,0.003538448,0.0005066447,0.004122887],"genre_scores_gemma":[0.9678382,0.001385198,0.01988462,0.000169446,0.00001513169,0.0001655945,0.005647614,0.0001224898,0.004771648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001198805,"threshold_uncertainty_score":0.004010379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01585252875225109,"score_gpt":0.2425979447541167,"score_spread":0.2267454160018656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}