{"id":"W3096622737","doi":"10.1016/j.jhazmat.2020.124440","title":"Feed-additive of bioengineering strain with surface-displayed laccase degrades sulfadiazine in broiler manure and maintains intestinal flora structure","year":2020,"lang":"en","type":"article","venue":"Journal of Hazardous Materials","topic":"Pharmaceutical and Antibiotic Environmental Impacts","field":"Environmental Science","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China","keywords":"Sulfadiazine; Broiler; Manure; Laccase; Food science; Chemistry; Microbiology; Feces; Escherichia coli; Antibiotics; Animal feed; Clostridia; Biology; Bacteria; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001250465,0.0004713913,0.000249534,0.0002057842,0.0001148853,0.0003530136,0.0002176436,0.0003008156,0.0009017638],"category_scores_gemma":[0.0001369368,0.0001113879,0.0002800307,0.0001612,0.0001383274,0.0002122094,0.0002241758,0.0004450481,0.0001920557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001486992,"about_ca_system_score_gemma":0.0001885925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009288804,"about_ca_topic_score_gemma":0.001543382,"domain_scores_codex":[0.9998123,0.00002023104,0.00001490968,0.00004331402,0.00005746631,0.00005188644],"domain_scores_gemma":[0.9998997,0.00001473989,0.00002871053,0.00001064593,0.00002001446,0.00002606424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009789579,0.00004857062,0.0001248063,0.00001414583,0.000002622824,0.0000191888,0.000005765871,0.00002621725,0.9990931,0.000009273481,0.000009578554,0.0005488969],"study_design_scores_gemma":[0.000003046941,0.000312766,0.001531222,0.000002873424,0.00001065888,0.00003160545,0.00002573801,0.0002533353,0.9975404,0.000005708248,0.0002801625,0.000002465669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983131,0.000164304,0.0009526636,0.00004100969,0.00002243689,0.000007395404,0.0001192337,0.00003345729,0.0003464517],"genre_scores_gemma":[0.9956765,0.0001566592,0.00168464,0.00002285506,0.00000600799,0.000007144742,0.0003665096,0.00001096602,0.002068759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009288804,"threshold_uncertainty_score":0.00301671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01342369868436328,"score_gpt":0.2314879470671743,"score_spread":0.218064248382811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}