{"id":"W3096630337","doi":"10.3390/biomedicines8110465","title":"FAM188B Expression Is Critical for Cell Growth via FOXM1 Regulation in Lung Cancer","year":2020,"lang":"en","type":"article","venue":"Biomedicines","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Center","keywords":"Gene knockdown; FOXM1; Downregulation and upregulation; Cancer research; Biology; Cell growth; Lung cancer; Survivin; Transcription factor; Cell cycle; Cell biology; Cancer; Apoptosis; Gene; Medicine; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005625487,0.0001108771,0.0001134619,0.0000499497,0.00003626678,0.000008319525,0.00007768265,0.0001304726,0.00006186319],"category_scores_gemma":[0.00006196591,0.0000991397,0.00004985412,0.0001223075,0.00006329383,0.000008325604,0.00001700049,0.00003652012,0.000002170855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000015245,"about_ca_system_score_gemma":0.00002709283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002801191,"about_ca_topic_score_gemma":0.000007478931,"domain_scores_codex":[0.9992206,0.00002207136,0.0001934835,0.0002884549,0.0001224176,0.0001529489],"domain_scores_gemma":[0.9996618,0.00001396337,0.00003806405,0.000103522,0.00009701394,0.00008564544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001286671,0.00002621921,0.006177418,0.0001825093,0.000004723428,3.708829e-7,0.0001620074,0.00000639992,0.9776198,0.00002479179,0.01523233,0.0004348177],"study_design_scores_gemma":[0.001301404,0.0002279951,0.02037926,0.00005666925,0.00002370082,8.166786e-7,0.00005938541,0.00445477,0.9548658,0.0001017621,0.01835949,0.0001690124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8360751,0.003269472,0.141579,0.01737372,0.0005633141,0.0007627001,0.00009999031,0.00004636185,0.0002302748],"genre_scores_gemma":[0.9970806,0.00006239014,0.0009053203,0.001039105,0.0005390838,0.00005714437,0.0001999717,0.0000181887,0.00009818445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1610055,"threshold_uncertainty_score":0.4042799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01612994952811025,"score_gpt":0.2954250104420273,"score_spread":0.2792950609139171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}