{"id":"W3096667661","doi":"10.1021/acs.orglett.0c03113","title":"Controllable Tandem [3+2] Cyclization of Aromatic Aldehydes with Maleimides: Rhodium(III)-Catalyzed Divergent Synthesis of Indane-Fused Pyrrolidine-2,5-dione","year":2020,"lang":"en","type":"article","venue":"Organic Letters","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Ministry of Education of the People's Republic of China; National Natural Science Foundation of China","keywords":"Indane; Chemistry; Pyrrolidine; Stereoselectivity; Tandem; Catalysis; Rhodium; Cascade reaction; Combinatorial chemistry; Organic chemistry; Medicinal chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002144869,0.0008679839,0.0002721344,0.000181465,0.0001192127,0.0002113688,0.0004007664,0.0002551516,0.001031475],"category_scores_gemma":[0.0001484389,0.0001861668,0.0002491503,0.0001566264,0.0002307992,0.0002773458,0.0003172719,0.0005088506,0.0004781316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002942308,"about_ca_system_score_gemma":0.0002769875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004493619,"about_ca_topic_score_gemma":0.001502223,"domain_scores_codex":[0.9998293,0.00001577428,0.00001302879,0.0000504852,0.0000341398,0.00005738815],"domain_scores_gemma":[0.9999101,0.000009453275,0.0000318867,0.00001269439,0.00001123669,0.00002455466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007065458,0.0000256541,0.00007941818,0.00007697481,0.000009744555,0.0001747189,0.00004178097,0.0002833084,0.9949747,0.0004378377,0.0000686893,0.003756479],"study_design_scores_gemma":[0.000007485929,0.000123196,0.0003600278,0.000002523203,0.000006993262,0.0001283847,0.000005790103,0.0005293521,0.9971289,0.00002540314,0.001672997,0.000008998728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9653464,0.00178967,0.02216985,0.00009205452,0.00008712214,0.0001444442,0.0003942739,0.0003724541,0.009603844],"genre_scores_gemma":[0.986656,0.0007438785,0.009336848,0.00003535566,0.00001099759,0.00004289654,0.00021831,0.00003793948,0.002917765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001031475,"threshold_uncertainty_score":0.003450692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01549443103943768,"score_gpt":0.2202790361116753,"score_spread":0.2047846050722376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}