{"id":"W3096717709","doi":"10.1182/blood-2020-140837","title":"CC-486 Prolongs Survival for Patients with Acute Myeloid Leukemia (AML) in Remission after Intensive Chemotherapy (IC) Independent of the Presence of Measurable Residual Disease (MRD) at Study Entry: Results from the QUAZAR AML-001 Maintenance Trial","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Myeloid leukemia; Medicine; Chemotherapy; Chemotherapy regimen; Internal medicine; Minimal residual disease; Oncology; Leukemia; Disease; Complete remission; Myeloid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008731559,0.0006548295,0.001279351,0.0002510187,0.0001886553,0.0005321484,0.0004715428,0.0005969984,0.001980034],"category_scores_gemma":[0.0007111226,0.0001785161,0.0007515584,0.0002822197,0.0004998554,0.0003796331,0.0002727216,0.00144737,0.0002942532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004768476,"about_ca_system_score_gemma":0.0005302156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005702309,"about_ca_topic_score_gemma":0.001646735,"domain_scores_codex":[0.9997728,0.0001032217,0.0000177186,0.00003703293,0.00002101457,0.00004822874],"domain_scores_gemma":[0.9993476,0.0001303241,0.0002030984,0.00004694696,0.00002479283,0.0002472531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8623433,0.008306077,0.01306443,0.0009113141,0.001552143,0.0001117921,0.0001473999,0.001335747,0.01868019,0.0001536922,0.001886458,0.09150743],"study_design_scores_gemma":[0.5140447,0.4031415,0.07257099,0.000108778,0.002013918,0.0003862658,0.00006889654,0.001402403,0.00339657,0.0002893671,0.002535014,0.00004154301],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965044,0.002243664,0.00007760501,0.0002000785,0.00004766501,0.0002077541,0.0002683141,0.00003043209,0.0004200116],"genre_scores_gemma":[0.9973091,0.001126072,0.0001770981,0.0002282569,0.0001082939,0.0001861357,0.0003980446,0.000005573369,0.0004613515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001980034,"threshold_uncertainty_score":0.006623864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01991898408853723,"score_gpt":0.2575425514884541,"score_spread":0.2376235673999168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}