{"id":"W3096751739","doi":"10.3390/cells9112434","title":"Nanotherapeutic Modulation of Human Neural Cells and Glioblastoma in Organoids and Monocultures","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Microglia; Organoid; Immune system; Cell biology; Astrocyte; Biology; Chemistry; Neuroscience; Inflammation; Central nervous system; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003547424,0.00009584925,0.0001160802,0.00005788972,0.0000574407,0.00003656339,0.00006576891,0.00003632322,0.00003579483],"category_scores_gemma":[0.00002120798,0.00009097524,0.00001520417,0.0001686635,0.00004956527,0.000124536,0.00003384324,0.00007471617,0.000006513623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003893229,"about_ca_system_score_gemma":0.000005756308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001475569,"about_ca_topic_score_gemma":0.000003510117,"domain_scores_codex":[0.9992315,0.00009033499,0.000196997,0.0002673393,0.000116636,0.00009715334],"domain_scores_gemma":[0.9997256,0.00004304955,0.00007424732,0.00008101644,0.00001253867,0.00006349204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001625955,0.00001184523,0.00004338212,0.00002081826,3.569012e-7,0.000004701611,0.0006279434,0.000328681,0.9977863,0.0006900051,0.00003110498,0.0004385544],"study_design_scores_gemma":[0.0003805913,0.0001660845,0.0004691645,0.000003563957,0.000002467714,0.000002630778,0.00001994424,0.02110703,0.9775102,0.00013922,0.0001199928,0.00007917907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991715,0.00001509555,0.00009363057,0.0003617612,0.00006553136,0.0001721357,0.000004472413,0.00003423771,0.00008162975],"genre_scores_gemma":[0.9983991,0.000032713,0.00005951184,0.001355866,0.00002453363,0.000002482743,4.492528e-7,0.00001272541,0.0001126575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02077835,"threshold_uncertainty_score":0.3709863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03119450905495607,"score_gpt":0.2455733512945569,"score_spread":0.2143788422396009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}