{"id":"W3096751739","doi":"10.3390/cells9112434","title":"Nanotherapeutic Modulation of Human Neural Cells and Glioblastoma in Organoids and Monocultures","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Microglia; Organoid; Immune system; Cell biology; Astrocyte; Biology; Chemistry; Neuroscience; Inflammation; Central nervous system; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001762633,0.0003630371,0.0003874752,0.0002436509,0.0001362701,0.0002099393,0.00014554,0.0002423153,0.0008975732],"category_scores_gemma":[0.0001032283,0.00009400953,0.0002876047,0.0002609797,0.0001240391,0.0001666688,0.0001900567,0.0002456724,0.0003230953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002385467,"about_ca_system_score_gemma":0.0001885533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001747696,"about_ca_topic_score_gemma":0.003110317,"domain_scores_codex":[0.9998105,0.00003288486,0.00002141927,0.00005452312,0.00005008268,0.00003059263],"domain_scores_gemma":[0.9999214,0.00001922625,0.00001395704,0.00001511554,0.000017457,0.0000128813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002604592,0.00009414279,0.0003360969,0.0002315116,0.00002123457,0.0001893878,0.00009148708,0.0004827695,0.9926494,0.0001389544,0.0002479625,0.005256644],"study_design_scores_gemma":[0.00001811474,0.0006017988,0.002718965,0.00001415481,0.00004015609,0.0002589557,0.0000663586,0.0009536712,0.9900162,0.00004716829,0.005255328,0.000009308568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9732861,0.009369305,0.01138894,0.0001324418,0.0001652057,0.0001874788,0.001721617,0.0001380408,0.003610813],"genre_scores_gemma":[0.9836992,0.003771913,0.008868524,0.00009102094,0.00001573126,0.0002383279,0.001272821,0.00002714106,0.002015494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001747696,"threshold_uncertainty_score":0.00347501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03119450905495607,"score_gpt":0.2455733512945569,"score_spread":0.2143788422396009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}