{"id":"W3096814327","doi":"10.1371/journal.pgen.1009184","title":"Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis","year":2020,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Fonds de Recherche du Québec - Santé; Cancer Research Society","keywords":"Biology; Anaphase-promoting complex; Mitosis; Meiosis; Cell biology; Cyclin; Cyclin B; Anaphase; Cyclin B1; Genetics; Cell cycle; Cyclin-dependent kinase 1; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007026399,0.0002693225,0.0001311203,0.0002672412,0.0003308305,0.0003310961,0.0001732573,0.0002481082,0.002654044],"category_scores_gemma":[0.00007440693,0.0001338359,0.0002120323,0.0001565614,0.0002244626,0.0001670494,0.0003537344,0.0004208746,0.0007096471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006269738,"about_ca_system_score_gemma":0.0003156454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00233215,"about_ca_topic_score_gemma":0.003718042,"domain_scores_codex":[0.9999434,0.000005546677,0.000002945958,0.00001704792,0.00001773258,0.00001326744],"domain_scores_gemma":[0.9999392,0.000005325138,0.00001413093,0.000005887211,0.000007838538,0.00002755277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000113012,0.0000140737,0.0004634511,0.0000758547,0.000005652479,0.000157322,0.00001318008,0.00004984874,0.9943823,0.0008761126,0.0003073862,0.00354179],"study_design_scores_gemma":[0.0000681775,0.0001289478,0.02492998,0.00003325395,0.00002245534,0.001403153,0.00005676882,0.0007522243,0.933812,0.0006012972,0.03817921,0.00001253984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9014656,0.03634162,0.0103031,0.0009371692,0.0004561336,0.0001526496,0.00141329,0.0005327057,0.04839776],"genre_scores_gemma":[0.9818552,0.004514081,0.001831885,0.0002000882,0.00003645069,0.00003724434,0.0006066049,0.00004412856,0.01087445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002654044,"threshold_uncertainty_score":0.008878648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02753833924493462,"score_gpt":0.2425732269483464,"score_spread":0.2150348877034118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}