{"id":"W3096865169","doi":"10.1182/blood-2020-136682","title":"Dabigatran Etexilate in Children with Venous Thromboembolism: Results of the Open-Label, Phase IIb/III, Randomized Diversity Clinical Trial","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Children's Hospital of Eastern Ontario; Hospital for Sick Children; University of Ottawa","funders":"","keywords":"Medicine; Dosing; Randomized controlled trial; Off-label use; Adverse effect; Data monitoring committee; Clinical endpoint; Dabigatran; Pediatrics; Internal medicine; Warfarin; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00292631,0.001165573,0.002254556,0.000286569,0.0004309714,0.0012553,0.0006052206,0.001359754,0.004640071],"category_scores_gemma":[0.004463561,0.0004174552,0.002108408,0.000432899,0.001081315,0.0009741195,0.0005440828,0.002090044,0.0005101218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009668441,"about_ca_system_score_gemma":0.001496138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009175675,"about_ca_topic_score_gemma":0.002184579,"domain_scores_codex":[0.9977742,0.00150934,0.0001669433,0.0002305393,0.0001542485,0.0001646594],"domain_scores_gemma":[0.9975907,0.0007089503,0.0008309794,0.0001761152,0.0001682704,0.0005249533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9671441,0.003586323,0.005026775,0.001256559,0.00283323,0.000139647,0.00009788477,0.0003544463,0.001457263,0.0003231271,0.002240692,0.01553994],"study_design_scores_gemma":[0.9588048,0.03300286,0.004792087,0.0001339651,0.0008136613,0.0001393239,0.00004435757,0.0001773454,0.0002347046,0.0001765635,0.001666932,0.00001342589],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.96706,0.01570228,0.0007416406,0.002019302,0.0005260762,0.005585875,0.00424507,0.00006236797,0.004057436],"genre_scores_gemma":[0.9738557,0.007205758,0.002420048,0.002251825,0.0007145289,0.007852679,0.003879574,0.00002423979,0.001795652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004640071,"threshold_uncertainty_score":0.0155226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.105850382356078,"score_gpt":0.3586811244581756,"score_spread":0.2528307421020975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}