{"id":"W3096886743","doi":"10.3390/cells9112408","title":"Characterization of Mutational Status, Spheroid Formation, and Drug Response of a New Genomically-Stable Human Ovarian Clear Cell Carcinoma Cell Line, 105C","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Western University; Juravinski Cancer Centre; McMaster University; Lawson Health Research Institute","funders":"","keywords":"Clear cell carcinoma; PTEN; Cell culture; Cancer research; Clear cell renal cell carcinoma; PI3K/AKT/mTOR pathway; Biology; Clear cell; Cell; Cancer; Carcinoma; Medicine; Renal cell carcinoma; Cell biology; Genetics; Pathology; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001042036,0.0001216616,0.0002700646,0.00005034206,0.00003875279,0.00001384298,0.00004601143,0.00005036921,0.0005038268],"category_scores_gemma":[0.00001204343,0.0001170302,0.00005467342,0.0001312222,0.00003492783,0.0001030781,0.00002919907,0.00006772936,0.00002961999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005798642,"about_ca_system_score_gemma":0.0002434866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000127042,"about_ca_topic_score_gemma":0.000004650336,"domain_scores_codex":[0.9990343,0.00005494675,0.000393886,0.0001974598,0.0001686392,0.0001507737],"domain_scores_gemma":[0.9992345,0.00005390494,0.000232661,0.0001528167,0.0001081903,0.0002179165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001337091,0.0002727106,0.006351708,0.0004053728,0.00002378174,0.00001005029,0.004845875,0.00004966244,0.984595,0.00005417678,0.001727396,0.0003271794],"study_design_scores_gemma":[0.003392112,0.0006301153,0.1448336,0.00003229884,0.000110926,0.000001816631,0.0002116824,0.0002467547,0.8457834,0.00001807044,0.004648066,0.00009120346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972776,0.0001840983,0.0004688513,0.00102025,0.00003662653,0.0004152617,0.0001061399,0.0000174039,0.0004738306],"genre_scores_gemma":[0.9960306,0.00006050623,0.002382447,0.0003102119,0.000091652,0.000007144743,0.000171534,0.00002716886,0.0009186793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1388116,"threshold_uncertainty_score":0.5516551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0157372718533717,"score_gpt":0.2289541448725656,"score_spread":0.2132168730191939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}