{"id":"W3096886743","doi":"10.3390/cells9112408","title":"Characterization of Mutational Status, Spheroid Formation, and Drug Response of a New Genomically-Stable Human Ovarian Clear Cell Carcinoma Cell Line, 105C","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Western University; Juravinski Cancer Centre; McMaster University; Lawson Health Research Institute","funders":"","keywords":"Clear cell carcinoma; PTEN; Cell culture; Cancer research; Clear cell renal cell carcinoma; PI3K/AKT/mTOR pathway; Biology; Clear cell; Cell; Cancer; Carcinoma; Medicine; Renal cell carcinoma; Cell biology; Genetics; Pathology; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001576775,0.000149236,0.000212691,0.00031423,0.000221046,0.0003482148,0.0001335087,0.0002736896,0.0007548792],"category_scores_gemma":[0.0001965734,0.00007851743,0.0001813743,0.0003103767,0.0001287252,0.0001258958,0.0001200403,0.0003040156,0.0002963784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003300287,"about_ca_system_score_gemma":0.0002426508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005062479,"about_ca_topic_score_gemma":0.005034236,"domain_scores_codex":[0.999804,0.00002004641,0.0000307883,0.00003860937,0.00008648274,0.00002016463],"domain_scores_gemma":[0.9998591,0.00003109372,0.00001893921,0.00003245949,0.00003378769,0.00002465599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004621991,0.0000499123,0.003017551,0.00002227295,0.000008492355,0.0000813914,0.0000562979,0.00016274,0.9939813,0.0001833617,0.0002452458,0.002145134],"study_design_scores_gemma":[0.00002963475,0.0007685116,0.09589736,0.000008830717,0.00005069621,0.001260352,0.0002087165,0.003996795,0.8874811,0.00006859707,0.0102073,0.00002219261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913492,0.0006688859,0.002728115,0.0001141026,0.00001614962,0.00007611781,0.002530376,0.00006663465,0.002450593],"genre_scores_gemma":[0.9864848,0.0004114016,0.003990659,0.00009718632,0.000005159408,0.00008616737,0.006941134,0.00002046635,0.001962945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005062479,"threshold_uncertainty_score":0.01006603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0157372718533717,"score_gpt":0.2289541448725656,"score_spread":0.2132168730191939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}