{"id":"W3097004036","doi":"10.1158/1078-0432.ccr-20-2558","title":"Mutational Landscape and Tumor Burden Assessed by Cell-free DNA in Diffuse Large B-Cell Lymphoma in a Population-Based Study","year":2020,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Centro de Investigación Biomédica en Red de Cáncer; Ministerio de Ciencia e Innovación; Canadian Institutes of Health Research; Generalitat de Catalunya","keywords":"Lymphoma; DNA; Population; Cell; Circulating tumor DNA; Cancer research; Biology; Cancer; Medicine; Computational biology; Genetics; Immunology; Environmental health","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001102968,0.0001460357,0.0004531617,0.0001452829,0.00006656262,0.00004777176,0.0001687557,0.00009120301,0.0002073175],"category_scores_gemma":[0.0008654877,0.0001203348,0.00006743086,0.0005379169,0.00004979174,0.00005454513,0.0001359841,0.0002852035,0.00002535099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002595894,"about_ca_system_score_gemma":0.0006386708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002452052,"about_ca_topic_score_gemma":0.001284932,"domain_scores_codex":[0.9972217,0.0004586585,0.0005883538,0.0005757601,0.0007497377,0.0004057886],"domain_scores_gemma":[0.9975781,0.00159001,0.00006724898,0.0002906423,0.0001195352,0.0003544435],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009474004,0.01698125,0.9768224,0.00009854509,0.00002104562,0.0005425404,0.0002776912,0.000007602242,0.00004649903,0.000007089526,0.003315307,0.0009326108],"study_design_scores_gemma":[0.08410899,0.001160412,0.9103566,0.00006520414,0.00002631389,6.942742e-7,0.000496021,0.002874758,0.0001375593,0.00003029168,0.0006344915,0.0001086256],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908058,0.0008968315,0.000001278322,0.006737225,0.00003866257,0.001113039,0.0001001228,0.00001900002,0.0002880373],"genre_scores_gemma":[0.9981388,0.00008255323,0.00004083377,0.0008830154,0.0001763275,0.0004564585,0.0001111859,0.00002448634,0.00008630075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08316159,"threshold_uncertainty_score":0.4907113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09376157918107385,"score_gpt":0.4439612368853415,"score_spread":0.3501996577042676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}