{"id":"W3097004036","doi":"10.1158/1078-0432.ccr-20-2558","title":"Mutational Landscape and Tumor Burden Assessed by Cell-free DNA in Diffuse Large B-Cell Lymphoma in a Population-Based Study","year":2020,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Centro de Investigación Biomédica en Red de Cáncer; Ministerio de Ciencia e Innovación; Canadian Institutes of Health Research; Generalitat de Catalunya","keywords":"Lymphoma; DNA; Population; Cell; Circulating tumor DNA; Cancer research; Biology; Cancer; Medicine; Computational biology; Genetics; Immunology; Environmental health","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000600721,0.0002691153,0.0003773128,0.0006376754,0.0003007571,0.000621577,0.0002294247,0.0004501452,0.0007685496],"category_scores_gemma":[0.001845949,0.0002829875,0.0002284513,0.000477983,0.0003298375,0.0004384005,0.0003131357,0.0004022831,0.0002287391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002015438,"about_ca_system_score_gemma":0.000147619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001050156,"about_ca_topic_score_gemma":0.0008821625,"domain_scores_codex":[0.999585,0.0001235237,0.00002872935,0.000147284,0.00007232848,0.00004322404],"domain_scores_gemma":[0.9993215,0.0001733675,0.0001819468,0.00008395826,0.00008843665,0.0001509084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001730951,0.00003837852,0.9979766,0.000003695305,0.0000458963,0.00011052,0.00004539603,0.00003648015,0.0008871303,0.000007143022,0.00002274895,0.0006528693],"study_design_scores_gemma":[0.00002402082,0.0002896087,0.9978077,0.000002472894,0.00004029293,0.001000173,0.000125958,0.0003562823,0.0001928035,0.00002461167,0.0001310655,0.000004940435],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999697,0.00006401226,0.00007890879,0.000007638637,0.000001134462,0.000003577829,0.00006194124,0.000001563345,0.00008422804],"genre_scores_gemma":[0.9998202,0.00002002115,0.00002712943,0.000008868999,0.00000272631,0.000002744908,0.00009157285,8.08985e-7,0.00002604001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001050156,"threshold_uncertainty_score":0.003176987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09376157918107385,"score_gpt":0.4439612368853415,"score_spread":0.3501996577042676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}