{"id":"W3097019221","doi":"10.1016/j.celrep.2020.108318","title":"A Broad Response to Intracellular Long-Chain Polyphosphate in Human Cells","year":2020,"lang":"en","type":"article","venue":"Cell Reports","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Proteome; Transcriptome; Cell biology; Biology; RNA; Intracellular; Polyphosphate; Biochemistry; Ectopic expression; Signal transduction; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001209194,0.0001791752,0.0002045408,0.0001538488,0.0001555871,0.0003368004,0.00005895552,0.0002726863,0.00292269],"category_scores_gemma":[0.000121215,0.00008652959,0.0001738824,0.0002246231,0.0001316274,0.0001296931,0.000189451,0.0004249561,0.0006918177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001686666,"about_ca_system_score_gemma":0.0001215013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003498658,"about_ca_topic_score_gemma":0.0004257651,"domain_scores_codex":[0.9997931,0.00003513568,0.00001483593,0.00005991893,0.00006316821,0.00003390942],"domain_scores_gemma":[0.9999182,0.00002780207,0.00001341285,0.00001172269,0.00001229068,0.00001647972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000101825,0.00001409255,0.0001836036,0.00002957233,0.000003154514,0.00006451071,0.00001904597,0.00002287988,0.998391,0.00002864907,0.0001038581,0.001037756],"study_design_scores_gemma":[0.00001896165,0.000381087,0.01167906,0.000006489053,0.00001379593,0.0005944854,0.00008632586,0.0006250664,0.98096,0.00007730279,0.005551009,0.000006419891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9775441,0.00527746,0.007023415,0.0004959936,0.0001036701,0.0001013797,0.002657236,0.000224232,0.006572396],"genre_scores_gemma":[0.9875284,0.001557988,0.003404653,0.0004592106,0.00002573013,0.0001077797,0.001788401,0.00002912382,0.005098658],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00292269,"threshold_uncertainty_score":0.009777367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01590890854267198,"score_gpt":0.2572103655484834,"score_spread":0.2413014570058114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}