{"id":"W3097023432","doi":"10.1128/aem.02183-20","title":"Repeated Oral Vaccination of Cattle with Shiga Toxin-Negative Escherichia coli O157:H7 Reduces Carriage of Wild-Type E. coli O157:H7 after Challenge","year":2020,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Institute of General Medical Sciences; National Institutes of Health; U.S. Department of Agriculture","keywords":"Carriage; Escherichia coli; Vaccination; Microbiology; Pathogen; Shiga toxin; Bloody diarrhea; Biology; Cattle Diseases; Diarrhea; Bacteria; Virology; Beef cattle; Enterobacteriaceae; Medicine; Gene; Animal science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003660404,0.0004440514,0.0007077655,0.0003078555,0.0001932992,0.0004011864,0.0003420455,0.000625316,0.001904687],"category_scores_gemma":[0.0003661922,0.0001876218,0.0002888503,0.0001316128,0.0003079514,0.0002405587,0.0001435287,0.0008765933,0.0002844588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005060353,"about_ca_system_score_gemma":0.0003904028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002120216,"about_ca_topic_score_gemma":0.003238282,"domain_scores_codex":[0.9996569,0.00005474351,0.00001617831,0.00008009412,0.00006606262,0.0001260317],"domain_scores_gemma":[0.9996818,0.00006337297,0.00007119577,0.00002156734,0.00004656841,0.0001155051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006480673,0.004158528,0.002029995,0.0001374264,0.00004769988,0.00003823531,0.0001142835,0.0001522079,0.9804975,0.00003512041,0.0001178025,0.006190563],"study_design_scores_gemma":[0.0008806715,0.1489648,0.0521181,0.00007031625,0.0002750426,0.000267496,0.0003272446,0.001430209,0.7937373,0.00007662199,0.001825393,0.00002680482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992448,0.0002530635,0.0001765427,0.00003195886,0.00002424309,0.0000164647,0.00004749973,0.00001268391,0.0001927815],"genre_scores_gemma":[0.9966816,0.0003437405,0.0005786488,0.00007163542,0.00002468821,0.00003743259,0.0002635728,0.000009794982,0.001988661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002120216,"threshold_uncertainty_score":0.006371856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008827858380454032,"score_gpt":0.213064100932167,"score_spread":0.204236242551713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}