{"id":"W3097068230","doi":"10.1139/cjpp-2020-0306","title":"Effect of high-fat diet on mechanosensitive transient receptor potential channel activation in vagal afferent neurons","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kingston General Hospital; Queen's University","funders":"","keywords":"Transient receptor potential channel; Mechanosensitive channels; TRPV4; TRPV1; Endocrinology; Internal medicine; Nodose Ganglion; TRPV; Stimulation; Chemistry; Extracellular; Nociceptor; Receptor; Vagus nerve; Nociception; Ion channel; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000150673,0.0003254458,0.0005008997,0.0002249234,0.0001559331,0.0003344555,0.0001765644,0.0004162944,0.001797789],"category_scores_gemma":[0.0002235502,0.0001744141,0.0003127079,0.0001705237,0.000371573,0.0003249726,0.0002532749,0.001008627,0.0001561745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002898733,"about_ca_system_score_gemma":0.0002304052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008438202,"about_ca_topic_score_gemma":0.00194462,"domain_scores_codex":[0.9998442,0.00002831254,0.00001795606,0.00003243611,0.00002336316,0.00005372587],"domain_scores_gemma":[0.9997774,0.00004264829,0.00004918432,0.00002607637,0.00002805125,0.00007669001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003484569,0.0002538016,0.0003682826,0.0000923226,0.00002598725,0.00006124363,0.00002201449,0.00002916037,0.9940124,0.00003655051,0.0000461358,0.001567571],"study_design_scores_gemma":[0.0002755232,0.005050251,0.03426057,0.00003666156,0.0001445125,0.0002716223,0.0001709715,0.0009377319,0.9570771,0.000128417,0.001622558,0.00002394544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998377,0.0006354372,0.0003255942,0.00009111145,0.00003853372,0.00001116006,0.0001658401,0.00001600756,0.0003393602],"genre_scores_gemma":[0.9948779,0.00109439,0.001294082,0.0001750897,0.00002046334,0.00007574111,0.000364828,0.00001969709,0.002077645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001797789,"threshold_uncertainty_score":0.006014228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01712136984535595,"score_gpt":0.2565392504096785,"score_spread":0.2394178805643225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}