{"id":"W3097097114","doi":"10.1182/blood-2020-134624","title":"High Doses of Targeted Radiation with Anti-CD45 Iodine (131I) Apamistamab [Iomab-B] Do Not Correlate with Incidence of Mucositis, Febrile Neutropenia or Sepsis in the Prospective, Randomized Phase 3 Sierra Trial for Patients with Relapsed or Refractory Acute Myeloid Leukemia","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Mucositis; Medicine; Neutropenia; Incidence (geometry); Febrile neutropenia; Sepsis; Internal medicine; Randomized controlled trial; Surgery; Radiation therapy; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003307166,0.0007679687,0.001391686,0.0002749604,0.0002557651,0.0009047906,0.0007303907,0.0007670011,0.001931571],"category_scores_gemma":[0.001630845,0.0003964395,0.001186934,0.0003497622,0.0009957758,0.0005996436,0.000391459,0.00198715,0.0003428395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004847643,"about_ca_system_score_gemma":0.0009829988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003493613,"about_ca_topic_score_gemma":0.001081416,"domain_scores_codex":[0.9986516,0.0009326986,0.00007691081,0.000140728,0.00007921174,0.0001189719],"domain_scores_gemma":[0.998364,0.0004014874,0.0005400332,0.0001698663,0.00004897349,0.0004756346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9514325,0.007789318,0.007607108,0.0003955808,0.001111124,0.00004253997,0.00007508855,0.0007087284,0.01383161,0.0001369172,0.0008649933,0.01600449],"study_design_scores_gemma":[0.6641536,0.3093773,0.01918424,0.00005054946,0.001631395,0.00015725,0.00003680663,0.0006734299,0.002956938,0.0001827934,0.001565381,0.00003033568],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951024,0.002369176,0.0003173931,0.0002043964,0.00009800792,0.0007244817,0.0002550765,0.00004604143,0.0008830422],"genre_scores_gemma":[0.9965717,0.0006963892,0.0005807223,0.0003652524,0.0001109682,0.000712549,0.0005177112,0.00001140008,0.0004333498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003307166,"threshold_uncertainty_score":0.01749015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01463495312699031,"score_gpt":0.2826821903523069,"score_spread":0.2680472372253166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}