{"id":"W3097160786","doi":"10.1182/blood-2020-140577","title":"Real-World Outcomes of Patients Treated with Single-Agent Ibrutinib for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): A Systematic Review and Meta-Analysis","year":2020,"lang":"en","type":"review","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Ibrutinib; Medicine; Internal medicine; Chronic lymphocytic leukemia; Discontinuation; Tolerability; Adverse effect; Oncology; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","metaepi_broad"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001074525,0.002116238,0.0279522,0.001388141,0.0001640791,0.0001150569,0.0009759651,0.0005724078,0.0001550512],"category_scores_gemma":[0.001155651,0.001291194,0.006526097,0.004103004,0.0003914613,0.0001164085,0.0004360555,0.0002970822,0.00006457444],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.1093499,"about_ca_system_score_gemma":0.05870941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001560348,"about_ca_topic_score_gemma":0.0003705515,"domain_scores_codex":[0.9895093,0.0008641142,0.004396061,0.002155363,0.001705665,0.001369526],"domain_scores_gemma":[0.9900694,0.002119509,0.003138597,0.002914186,0.000826179,0.0009321122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.00008147648,0.0004022823,0.00001470108,0.7154813,0.2822251,0.000213863,0.00003614005,0.000003286741,2.348865e-7,0.00001856334,0.00005932278,0.001463724],"study_design_scores_gemma":[0.02918981,0.001307587,0.00001065556,0.06650368,0.892992,0.0003172434,0.00000910997,0.0003328582,0.00002229684,0.000001766934,0.008314459,0.0009985205],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004098988,0.9788938,0.00002092984,0.00003422341,0.00003378923,0.01921242,0.0008963008,0.0002006914,0.0002979968],"genre_scores_gemma":[0.0007445356,0.9889469,0.0005900615,0.0002653623,0.00007830215,0.004739485,0.001369947,0.0004155795,0.002849824],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6489776,"threshold_uncertainty_score":0.9991579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08689948057481388,"score_gpt":0.3368523544679209,"score_spread":0.2499528738931071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}