{"id":"W3097160786","doi":"10.1182/blood-2020-140577","title":"Real-World Outcomes of Patients Treated with Single-Agent Ibrutinib for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): A Systematic Review and Meta-Analysis","year":2020,"lang":"en","type":"review","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Ibrutinib; Medicine; Internal medicine; Chronic lymphocytic leukemia; Discontinuation; Tolerability; Adverse effect; Oncology; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01590553,0.002261534,0.01801859,0.01238426,0.0006320315,0.003416618,0.002006367,0.001926457,0.002713252],"category_scores_gemma":[0.03774729,0.00140462,0.03260234,0.01210737,0.0007460109,0.001812594,0.001775876,0.001379292,0.0002530273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003166384,"about_ca_system_score_gemma":0.005101355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006462078,"about_ca_topic_score_gemma":0.01421499,"domain_scores_codex":[0.9842126,0.006490631,0.005756622,0.001379908,0.001775826,0.0003843981],"domain_scores_gemma":[0.9728707,0.01832397,0.005560388,0.0007673514,0.002150312,0.0003272033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0009036522,0.0000208869,0.004088193,0.5075578,0.4769954,0.0001185854,0.0001165878,0.0004157857,0.0002088428,0.0001130003,0.0005088821,0.008952341],"study_design_scores_gemma":[0.0003204604,0.000173155,0.004520497,0.05139948,0.9407771,0.0001360492,0.0000801876,0.0001684306,0.000112063,0.0001827802,0.002097341,0.00003248424],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005427895,0.9919926,0.0004953897,0.0002438615,0.00009924408,0.0003549041,0.001111553,0.00001975199,0.0002548684],"genre_scores_gemma":[0.2083714,0.7836011,0.002986055,0.0009164722,0.0002030071,0.001788844,0.00182292,0.0000358484,0.0002742817],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01801859,"threshold_uncertainty_score":0.08411747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08689948057481388,"score_gpt":0.3368523544679209,"score_spread":0.2499528738931071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}