{"id":"W3097446545","doi":"10.1038/s41598-020-75621-5","title":"Functional interaction between Ghrelin and GLP-1 regulates feeding through the vagal afferent system","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Toronto General Hospital","funders":"Japan Society for the Promotion of Science; University of Miyazaki; Core Research for Evolutional Science and Technology; Japan Agency for Medical Research and Development","keywords":"Ghrelin; Orexigenic; Internal medicine; Anorectic; Endocrinology; Growth hormone secretagogue receptor; Glucagon-like peptide-1; Receptor; Secretagogue; Nodose Ganglion; Biology; Hormone; Neuropeptide; Chemistry; Vagus nerve; Neuropeptide Y receptor; Medicine; Food intake","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109567,0.0001396594,0.0001787189,0.0000777526,0.00009318289,0.000179738,0.0001132729,0.0002205946,0.0009653456],"category_scores_gemma":[0.000123136,0.00008020555,0.0001257366,0.00004696869,0.0002201972,0.0001816616,0.0001607601,0.0003713451,0.0001184771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001791757,"about_ca_system_score_gemma":0.0001134156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000249291,"about_ca_topic_score_gemma":0.0002806021,"domain_scores_codex":[0.9999466,0.00001461934,0.000002965196,0.000007781224,0.000012972,0.00001497028],"domain_scores_gemma":[0.9999592,0.000008602327,0.000009524206,0.000002121766,0.000005073036,0.00001543284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000236803,0.00001737966,0.000382873,0.00002893816,0.000005016107,0.00005588259,0.000009069996,0.00003685728,0.9976203,0.0001164265,0.00001586631,0.001474677],"study_design_scores_gemma":[0.0001264644,0.002459604,0.127092,0.00003506723,0.00008730978,0.001049789,0.0001566611,0.003976915,0.860551,0.0007392218,0.003707247,0.00001865875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952041,0.00186786,0.001584851,0.00008729602,0.00002202206,0.00001105455,0.00003743735,0.00001239177,0.001173028],"genre_scores_gemma":[0.9967192,0.0007257805,0.001619775,0.00006738069,0.00001871276,0.00001958952,0.00005530915,0.000002941022,0.0007714066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009653456,"threshold_uncertainty_score":0.003229439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06046959507743686,"score_gpt":0.2653631495281011,"score_spread":0.2048935544506643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}