{"id":"W3097670425","doi":"10.1136/annrheumdis-2020-eular.1044","title":"OP0306 CD11C-SPECIFIC ABLATION OF SHP1 INDUCES AUTOIMMUNE SIALADENITIS SIMILAR TO SJÖGREN'S SYNDROME","year":2020,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Pfizer","keywords":"CD11c; Protein tyrosine phosphatase; Conditional gene knockout; Immune system; Immunology; Autoimmunity; Biology; Medicine; Cell biology; Phenotype; Signal transduction; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009808278,0.0001673373,0.0004787972,0.00006660994,0.0001044338,0.000009125861,0.0004839392,0.0001143688,0.0008711215],"category_scores_gemma":[0.0002658454,0.0001218762,0.0002156886,0.0002942792,0.0002196334,0.00006873097,0.0001713825,0.0001133075,0.00009689681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000825349,"about_ca_system_score_gemma":0.00007051302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007144101,"about_ca_topic_score_gemma":0.000003210394,"domain_scores_codex":[0.9987481,0.0002112937,0.0004939876,0.0002272878,0.00007011555,0.0002492488],"domain_scores_gemma":[0.9990148,0.0001550317,0.0003122861,0.0003525528,0.0001176962,0.00004764352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002518197,0.002180707,0.02862271,0.002028536,0.004466918,0.00002733228,0.01514001,0.001488394,0.4977825,0.008294728,0.17455,0.2629],"study_design_scores_gemma":[0.001420014,0.001348246,0.8695801,0.0008011707,0.0001991286,0.00005239801,0.001169751,0.00001959033,0.1067977,0.002168611,0.01595403,0.0004893405],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845796,0.007308104,0.00003605209,0.006864657,0.0003996087,0.0003081468,0.0002096085,0.00003621748,0.0002579889],"genre_scores_gemma":[0.9986212,0.0005086908,0.00002484115,0.0006288064,0.00001354294,0.00002231597,0.0000425201,0.00001431968,0.0001238201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8409573,"threshold_uncertainty_score":0.953817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04607562992102936,"score_gpt":0.2679257322105422,"score_spread":0.2218501022895129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}