{"id":"W3097670425","doi":"10.1136/annrheumdis-2020-eular.1044","title":"OP0306 CD11C-SPECIFIC ABLATION OF SHP1 INDUCES AUTOIMMUNE SIALADENITIS SIMILAR TO SJÖGREN'S SYNDROME","year":2020,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Pfizer","keywords":"CD11c; Protein tyrosine phosphatase; Conditional gene knockout; Immune system; Immunology; Autoimmunity; Biology; Medicine; Cell biology; Phenotype; Signal transduction; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001920458,0.0004640761,0.0002841596,0.0003801711,0.0002220551,0.0003509357,0.0002675558,0.0005780741,0.001742999],"category_scores_gemma":[0.0001740708,0.0002362826,0.0004518392,0.0002047342,0.0005325633,0.0002245959,0.0002514616,0.001367444,0.0003771312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000353613,"about_ca_system_score_gemma":0.0002724498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001007767,"about_ca_topic_score_gemma":0.00152798,"domain_scores_codex":[0.9997033,0.00004186647,0.00002927191,0.00004435505,0.00006947583,0.0001115637],"domain_scores_gemma":[0.9997455,0.00005612932,0.00004803102,0.00003271304,0.00001191531,0.0001056142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004753824,0.0002031911,0.000326103,0.00002698822,0.00001198567,0.0006842077,0.00002078997,0.0001291699,0.9968333,0.0002760883,0.0001414556,0.0008714007],"study_design_scores_gemma":[0.0003933028,0.002314844,0.01919162,0.00001002897,0.00005909721,0.003930779,0.0001481335,0.003157143,0.9674191,0.0002671231,0.003093849,0.0000151735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967699,0.0002605242,0.0006023361,0.000114752,0.00006628365,0.00002953527,0.0002341745,0.00007290062,0.001849585],"genre_scores_gemma":[0.9971645,0.0001629809,0.0003936485,0.00007023231,0.00001627904,0.00002867506,0.0002211648,0.00001884131,0.001923584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001742999,"threshold_uncertainty_score":0.005830884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04607562992102936,"score_gpt":0.2679257322105422,"score_spread":0.2218501022895129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}