{"id":"W3097692415","doi":"10.1016/j.pnpbp.2020.110164","title":"High genes: Genetic underpinnings of cannabis use phenotypes","year":2020,"lang":"en","type":"review","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cannabis; Heritability; Abstinence; Phenotype; Effects of cannabis; Cannabis Dependence; Candidate gene; Genome-wide association study; Craving; Psychology; Drug; Gene; Biology; Genetics; Psychiatry; Addiction; Cannabidiol; Single-nucleotide polymorphism; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002312843,0.0007545276,0.0009100084,0.0007667917,0.0001035539,0.0005906015,0.0005026895,0.0007632367,0.003023727],"category_scores_gemma":[0.0004750668,0.0001488813,0.0003565188,0.0009002661,0.0002906637,0.000277748,0.0004108493,0.0007727491,0.0006050472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003124076,"about_ca_system_score_gemma":0.0006500357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00207397,"about_ca_topic_score_gemma":0.003137639,"domain_scores_codex":[0.9999092,0.00001615451,0.00001067689,0.00002739654,0.00002500323,0.00001155707],"domain_scores_gemma":[0.9998461,0.00009212436,0.00002486813,0.000004344056,0.00002074514,0.00001170113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003718575,0.00005394096,0.003964217,0.009577928,0.0006401919,0.001074077,0.00008156883,0.0005424522,0.007096017,0.006537672,0.01432316,0.9557368],"study_design_scores_gemma":[0.0002040103,0.0001629174,0.04025794,0.008808405,0.002859376,0.008393288,0.0002843938,0.0005889114,0.003330637,0.02291797,0.9120957,0.00009646777],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001364965,0.9956979,0.0004706699,0.0006144172,0.0001504272,0.000004886476,0.0001382468,0.00001696845,0.001541667],"genre_scores_gemma":[0.01119549,0.9860672,0.000662593,0.0004391412,0.0002541072,0.00001033226,0.0002324778,0.000004289678,0.001134396],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003023727,"threshold_uncertainty_score":0.01011533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05197548721330655,"score_gpt":0.3805966328528066,"score_spread":0.3286211456395001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}