{"id":"W3097825419","doi":"10.1093/biolre/ioaa206","title":"Dynamics in the expression of epigenetic modifiers and histone modifications in perinatal rat germ cells during de novo DNA methylation†","year":2020,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Armand-Frappier Foundation","keywords":"Biology; Histone methyltransferase; Epigenomics; Histone methylation; DNA methylation; Epigenetics; Histone; Histone code; Reprogramming; Cancer epigenetics; EZH2; Epigenetic regulation of neurogenesis; Histone H2A; Molecular biology; Cell biology; Genetics; Gene expression; DNA; Cell; Gene; Nucleosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009755005,0.0001402955,0.0001549385,0.0003822389,0.00008444805,0.0002077121,0.0001339355,0.0001264898,0.0007662322],"category_scores_gemma":[0.00009739631,0.0001213884,0.0001390479,0.0001812822,0.0001508977,0.0001699879,0.0001973088,0.000286786,0.0001885785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001451775,"about_ca_system_score_gemma":0.0001639924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008577425,"about_ca_topic_score_gemma":0.001083868,"domain_scores_codex":[0.9999262,0.000004839596,0.000005310797,0.00002380111,0.000020194,0.00001964013],"domain_scores_gemma":[0.999872,0.00001180504,0.00004417975,0.00001059654,0.00002421987,0.00003716751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001200056,0.000006708163,0.004537527,0.00002427196,0.000006484969,0.00005431993,0.00004733673,0.00002937439,0.9924199,0.00008136234,0.00001366944,0.002659026],"study_design_scores_gemma":[0.00001047373,0.0003681874,0.2532282,0.00001454115,0.00004218397,0.000330493,0.0002622942,0.0006229092,0.7429576,0.0001297203,0.002019651,0.0000138005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995177,0.001344477,0.002295932,0.0000199369,0.000007001325,0.000008532986,0.0004064058,0.00003990572,0.0007007909],"genre_scores_gemma":[0.9934567,0.001232318,0.002000477,0.00003865634,0.000006009306,0.00003077249,0.0006239174,0.00002053285,0.002590633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008577425,"threshold_uncertainty_score":0.002563238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01675137753651895,"score_gpt":0.2728227896206262,"score_spread":0.2560714120841072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}