{"id":"W3097857700","doi":"10.1182/blood-2020-142565","title":"Effect of Pembrolizumab (Pembro) Monotherapy Versus Brentuximab Vedotin (BV) on Patients (Pts) with Relapsed/Refractory Classical Hodgkin Lymphoma (R/R cHL): Exploratory Analysis of the Randomized, Phase 3 Keynote-204 Study By Prior Lines of Therapy","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; Princess Margaret Cancer Centre","funders":"","keywords":"Brentuximab vedotin; Pembrolizumab; Medicine; Internal medicine; Classical Hodgkin lymphoma; Refractory (planetary science); Oncology; Phases of clinical research; Lymphoma; Hodgkin lymphoma; Clinical trial; Cancer; Materials science; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001968063,0.001202028,0.001785597,0.0003326455,0.0003056644,0.0007908533,0.0007471072,0.0009147204,0.003898282],"category_scores_gemma":[0.001612935,0.0005228417,0.001684453,0.0002770966,0.0008585528,0.0009545762,0.0004310489,0.002512343,0.0005692651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001009261,"about_ca_system_score_gemma":0.001152435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005570137,"about_ca_topic_score_gemma":0.002295,"domain_scores_codex":[0.9992616,0.0004725156,0.00003813158,0.00008933571,0.00003592291,0.0001024839],"domain_scores_gemma":[0.9986956,0.0004340461,0.0003105492,0.00008461619,0.00003951829,0.000435845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.968438,0.008478566,0.001123977,0.0002893455,0.0006908732,0.00003983879,0.00005634525,0.0006591076,0.004704712,0.0000655449,0.0005062295,0.01494752],"study_design_scores_gemma":[0.5881371,0.3996617,0.007655684,0.0000406415,0.0009121237,0.0000786904,0.00004060617,0.000865904,0.001661133,0.0001915488,0.0007296411,0.00002522062],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964046,0.001119316,0.000182653,0.0001984829,0.00008301328,0.0006920479,0.0004984332,0.00003629135,0.0007850864],"genre_scores_gemma":[0.9966349,0.000574722,0.0005023941,0.0002556826,0.0001302623,0.0006650168,0.0004464129,0.000009457077,0.0007813102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003898282,"threshold_uncertainty_score":0.01304108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01427175682008934,"score_gpt":0.2743418253335899,"score_spread":0.2600700685135006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}